Ross McQueenie

TL;DR: Efforts to identify, manage, and prevent frailty should include middle-aged individuals with multimorbidity, in whom frailty is significantly associated with mortality, even after adjustment for number of long-term conditions, sociodemographics, and lifestyle.

TL;DR: Type, as opposed to number, of LTCs may have an important role in understanding the relationship between multimorbidity and mortality and had a greater relative impact on all-cause mortality in middle-aged as well as older populations, particularly males, which deserves exploration.

TL;DR: Patients with a greater number of long-term conditions had an increased risk of missing general practice appointments despite controlling for number of appointments made, particularly among patients with mental health conditions.

TL;DR: The findings that both patient and practice characteristics contribute to non-attendance of general practice appointments raise important questions for both the management of patients who miss multiple appointments and the effectiveness of existing strategies that aim to increase attendance.

TL;DR: Being non-white, most socioeconomically deprived, BMI ≥40 kg/m2, and reduced renal function were associated with the highest risk of COVID-19 infection, and increasing multimorbidity and polypharmacy are associated with a higher risk of developing CO VID-19.