R
Ruben Isacson
Publications - 1
Citations - 126
Ruben Isacson is an academic researcher. The author has contributed to research in topics: Nitazoxanide & Population. The author has an hindex of 1, co-authored 1 publications receiving 98 citations.
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Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer
Wojciech Senkowski,Xiaonan Zhang,Maria Hägg Olofsson,Ruben Isacson,Urban Höglund,Mats G. Gustafsson,Peter Nygren,Stig Linder,Rolf Larsson,Mårten Fryknäs +9 more
TL;DR: It is reported that the FDA-approved anthelmintic drug nitazoxanide could be a potential candidate for advancement into cancer clinical trials and it is shown that all five compounds inhibit mitochondrial respiration, suggesting that cancer cells in low glucose concentrations depend on oxidative phosphorylation rather than solely glycolysis.