R
Rui Xiong
Researcher at Wuhan University
Publications - 19
Citations - 727
Rui Xiong is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 12 publications receiving 354 citations.
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Journal ArticleDOI
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice
TL;DR: In this article, macrophage-specific NLRP3 knockout mice were used to explore the mechanism of PM2.5-induced lung injury in terms of inflammatory response, oxidative stress, and apoptosis levels, including the relationship between these effects and pyroptosis.
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CircC3P1 attenuated pro-inflammatory cytokine production and cell apoptosis in acute lung injury induced by sepsis through modulating miR-21.
Wenyang Jiang,Jie Ren,Xinghua Zhang,Zilong Lu,Haojie Feng,Xiaoli Yao,Donghang Li,Rui Xiong,Tao Fan,Qing Geng +9 more
TL;DR: CircC3P1 attenuated pro‐inflammatory cytokine production and cell apoptosis in ALI induced by sepsis through modulating miR‐21, indicating that circC 3P1 is a promising therapeutic biomarker for sepsi‐induced ALI.
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Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation
TL;DR: MF protects against lung injury and inflammatory response by inhibiting NLRP3 inflammasome activation in a NF-κB-dependent manner in macrophages, which provides a promising therapeutic candidate for the treatment of lung injury.
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Ferroptosis: A New Promising Target for Lung Cancer Therapy.
TL;DR: Ferroptosis is a new type of regulatory cell death that differs from autophagy, apoptosis, necrosis, and pyroptoses; it is caused primarily by the accumulation of iron and lipid peroxides in the cell.
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Comparison of clinical characteristics of COVID-19 between elderly patients and young patients: a study based on a 28-day follow-up.
Lin Zhang,Tao Fan,Shuo Yang,Haojie Feng,Bo Hao,Zilong Lu,Rui Xiong,Xiaokang Shen,Wenyang Jiang,Wei Wang,Qing Geng +10 more
TL;DR: Overall, the research compared the clinical characteristics of the two populations with different immune status and illustrated differentiated risk factors for death in them.