R
Ruirui Ji
Researcher at University of Tennessee Health Science Center
Publications - 5
Citations - 1513
Ruirui Ji is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: microRNA & Cellular differentiation. The author has an hindex of 5, co-authored 5 publications receiving 1452 citations.
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Journal ArticleDOI
MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation
Ruirui Ji,Yunhui Cheng,Junming Yue,Jian Yang,Xiaojun Liu,He Chen,David B. Dean,Chunxiang Zhang +7 more
TL;DR: The results suggest that miRNAs are novel regulatory RNAs for neointimal lesion formation and may be a new therapeutic target for proliferative vascular diseases such as atherosclerosis, postangioplasty restenosis, transplantation arteriopathy, and stroke.
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MicroRNAs Are Aberrantly Expressed in Hypertrophic Heart : Do They Play a Role in Cardiac Hypertrophy?
Yunhui Cheng,Ruirui Ji,Junming Yue,Jian Yang,Xiaojun Liu,He Chen,David B. Dean,Chunxiang Zhang +7 more
TL;DR: It is demonstrated that miRNAs are aberrantly expressed in hypertrophic mouse hearts, and modulating miR-21 expression via antisense-mediated depletion (knockdown) had a significant negative effect on cardiomyocyte hypertrophy.
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Novel model of inflammatory neointima formation reveals a potential role of myeloperoxidase in neointimal hyperplasia
TL;DR: The first direct in vivo demonstration of neointimal formation induced by a product of the inflammatory cascade is demonstrated, suggesting that MPO may be a mediator for pathological neointima growth.
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l-Arginine Chlorination Results in the Formation of a Nonselective Nitric-Oxide Synthase Inhibitor
TL;DR: It is found that cl-l-Arg had a direct inhibitory effect on the activity of NOS, and might serve as a novel endogenous NOS inhibitor and an important mediator for vascular dysfunction under inflammatory conditions such as atherosclerosis.
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The early- and late stages in phenotypic modulation of vascular smooth muscle cells: differential roles for lysophosphatidic acid.
Huazhang Guo,Natalia Makarova,Yunhui Cheng,Shuyu E,Ruirui Ji,Chunxiang Zhang,Patricia L. Farrar,Gabor Tigyi +7 more
TL;DR: The present results indicate that LPA, serum, dissociation of VSMC, IGF-I, p38, ERK1/2, LPA1, and LPA2 are not causative factors of early PM ofVSMC.