R
Ruth M. Lunn
Researcher at National Institutes of Health
Publications - 41
Citations - 4125
Ruth M. Lunn is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 22, co-authored 35 publications receiving 3759 citations. Previous affiliations of Ruth M. Lunn include Research Triangle Park & Columbia University.
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Journal Article
XRCC1 polymorphisms : effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency
TL;DR: The results suggest that the Arg399Gln amino acid change may alter the phenotype of the XRCC1 protein, resulting in deficient DNA repair.
Journal ArticleDOI
XPD polymorphisms: effects on DNA repair proficiency
Ruth M. Lunn,Kathy J. Helzlsouer,Ram Parshad,David M. Umbach,Emily L. Harris,Katherine K. Sanford,Douglas A. Bell +6 more
TL;DR: It is suggested that the Lys751 (common) allele may alter the XPD protein product resulting in sub-optimal repair of X-ray-induced DNA damage.
Journal ArticleDOI
Cadmium-induced Cancers in Animals and in Humans
TL;DR: Most cadmium used in the United States is a byproduct from the smelting of zinc, lead, or copper ores, and is used to manufacture batteries, and the mechanism of carcinogenicity appears to be multifactorial.
Polymorphisms In The DNA Repair Gene Xrcc1 And Breast Cancer
Douglas A. Bell,Eric J. Duell,Allison Eaton,Ruth M. Lunn,Robert C. Millikan,Harvey W. Mohrenweiser,Beth Newman,Gary S. Pittman,Chiu-Kit Tse,Scott Winkel +9 more
TL;DR: The results suggest that XRRC1 codon 399 genotype may influence breast cancer risk, perhaps by modifying the effects of environmental exposures.
Journal Article
Polymorphisms In The DNA Repair Gene Xrcc1 And Breast Cancer
Eric J. Duell,Robert C. Millikan,Gary S. Pittman,Scott Winkel,Ruth M. Lunn,Chiu-Kit Tse,Allison Eaton,Harvey W. Mohrenweiser,Beth Newman,Douglas A. Bell +9 more
TL;DR: This paper examined the association of polymorphisms in XRCC1 (codon 194 Arg-->Trp and codon 399 Arg-->Gln) and breast cancer in the Carolina Breast Cancer Study, a population-based case-control study in North Carolina.