R
Ryan M. Porter
Researcher at University of Arkansas for Medical Sciences
Publications - 43
Citations - 1861
Ryan M. Porter is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Mesenchymal stem cell & Cartilage. The author has an hindex of 22, co-authored 39 publications receiving 1553 citations. Previous affiliations of Ryan M. Porter include Beth Israel Deaconess Hospital & Virginia Tech.
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Journal ArticleDOI
Interleukin‐1β and tumor necrosis factor α inhibit chondrogenesis by human mesenchymal stem cells through NF‐κB–dependent pathways
N. Wehling,Glyn D. Palmer,Carmencita Pilapil,Fangjun Liu,James W. Wells,P. E. Muller,Christopher H. Evans,Ryan M. Porter +7 more
TL;DR: Cell-based repair of lesions in articular cartilage will be compromised in inflamed joints and strategies for enabling repair under these conditions include the use of specific antagonists of individual pyrogens, such as IL-1beta and TNFalpha, or the targeting of important intracellular mediators,such as NF-kappaB.
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Facilitated endogenous repair: making tissue engineering simple, practical, and economical.
Christopher H. Evans,Glyn D. Palmer,Arnulf Pascher,Ryan M. Porter,Francois N. K. Kwong,Elvire Gouze,Jean Noel Gouze,Fangjun Liu,Andre F. Steinert,Oliver B. Betz,Volker M. Betz,Mark S. Vrahas,Steven C. Ghivizzani +12 more
TL;DR: Facilitated endogenous repair is a novel approach to tissue engineering that avoids the ex vivo culture of autologous cells and the need for manufactured scaffolds, while minimizing the number and invasiveness of associated clinical procedures.
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Osteogenic Potential of Reamer Irrigator Aspirator (RIA) Aspirate Collected from Patients Undergoing Hip Arthroplasty
Ryan M. Porter,Fangjun Liu,Fangjun Liu,Carmencita Pilapil,Carmencita Pilapil,Oliver B. Betz,Oliver B. Betz,Mark S. Vrahas,Mark S. Vrahas,Mitchel B. Harris,Mitchel B. Harris,Christopher H. Evans +11 more
TL;DR: Filtrate cells were more sensitive to seeding density during osteogenic culture but had similar capacity for chondrogenesis, and these results suggest using RIA aspirate to develop improved, clinically expeditious, cost‐effective technologies for accelerating the healing of bone and other musculoskeletal tissues.
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Effect of dexamethasone withdrawal on osteoblastic differentiation of bone marrow stromal cells
TL;DR: Results indicate that dexamethasone acts at both early and late stages to direct proliferative osteoprogenitor cells toward terminal maturation.
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Electrostatic interactions enable rapid penetration, enhanced uptake and retention of intra-articular injected avidin in rat knee joints.
TL;DR: Avidin penetrated the full thickness of articular cartilage within 6 h, with a half‐life of 29’h, and stayed inside the joint for 7 days after i.a. injection, and Avidin doses up to at least 1 µM did not affect bovine cartilage explant cell viability, matrix catabolism or biosynthesis.