Ryan S. Noyce

TL;DR: It is demonstrated that wild type measles virus infects primary airway epithelial cells grown in fetal calf serum and many adenocarcinoma cell lines of the lung, breast, and colon and several strains of measles virus were shown to use PVRL4 as a receptor.

TL;DR: It is demonstrated that HSV-1 modifies the IRF3 pathway in a manner different from that of the small RNA viruses most commonly studied, and that the RING finger domain of ICP0 is essential for this activity.

TL;DR: It is shown that the entry of enveloped virus particles from diverse virus families elicits a similar innate response to IRF3, but not IRF1, IRF7, or IRF9, and that subsequent virus replication results in posttranslational modification of IRf3, such as hyperphosphorylation, depending on the nature of the incoming virus.

TL;DR: This work believes this is the first complete synthesis of a poxvirus using synthetic biology approaches and supports further development of scHPXV as a novel replication-proficient smallpox vaccine.

TL;DR: It is suggested that the hydrolyzable tannins CHLA and PUG may be useful as competitors for glycosaminoglycans in the management of HSV-1 infections and that they may help reduce the risk for development of viral drug resistance during therapy with nucleoside analogues.