S. Gholampourkashi

TL;DR: Accurate modeling of the full‐width‐half‐maximum (FWHM) of the primary photon source as well as the MLC leaf design (leaf bank rotation, etc.) is essential for accurate calculations of dose delivered by small radiation fields when using virtual source or MC models of the beam.

TL;DR: The authors' 4D Monte Carlo method using defDOSXYZnrc can be used to accurately calculate the dose distribution in continuously moving anatomy for various treatment techniques and, if extended to deformable anatomies, can be use to reconstruct patient delivered dose for use in adaptive radiation therapy.

TL;DR: The deformable lung phantom presented realistic and reproducible motion characteristics and its use for verification of 4D dose calculations was demonstrated, demonstrating the 4DMC method is capable of accurate calculations of the realistic dose delivered to a moving and deforming anatomy during static and dynamic beam delivery techniques.

TL;DR: In small-field radiation therapy treatment planning, it is important to properly account for LBROT as an input parameter for MC dose calculations with the Elekta Agility multi-leaf collimator for Monte Carlo simulations.

TL;DR: 4DMC method, combined with RADPOS, can accurately simulate realistic dose deliveries to a deforming anatomy moving with realistic breathing traces and is shown to accurately predict the sensitivity of delivered dose to the starting phase of breathing motions.