S
S Gillis
Researcher at Amgen
Publications - 25
Citations - 2981
S Gillis is an academic researcher from Amgen. The author has contributed to research in topics: Interleukin 2 & Histamine. The author has an hindex of 19, co-authored 25 publications receiving 2956 citations. Previous affiliations of S Gillis include Johns Hopkins University.
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Journal ArticleDOI
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor after Autologous Bone Marrow Transplantation for Lymphoid Cancer
John Nemunaitis,John Nemunaitis,John Nemunaitis,SN Rabinowe,Jack W. Singer,Jack W. Singer,Jack W. Singer,Philip J. Bierman,Julie M. Vose,Arnold S. Freedman,Nicole Onetto,S Gillis,Dagmar Oette,Morris S. Gold,C. Dean Buckner,C. Dean Buckner,John A. Hansen,John A. Hansen,Jerome Ritz,Frederick R. Appelbaum,Frederick R. Appelbaum,James O. Armitage,Lee M. Nadler +22 more
TL;DR: The patients given rhGM-CSF had a recovery of the neutrophil count to 500×106 per liter 7 days earlier than the patients who received placebo, suggesting that recombinant human granulocytemacrophage colony-stimulating factor may accelerate neutrophIL recovery and thereby reduce complications in patients after autologous bone marrow transplantation.
Journal Article
The human recombinant c-kit receptor ligand, rhSCF, induces mediator release from human cutaneous mast cells and enhances IgE-dependent mediator release from both skin mast cells and peripheral blood basophils.
Michele Columbo,E. Horowitz,Luis M. Botana,Donald W. MacGlashan,Bruce S. Bochner,S Gillis,Krisztina M. Zsebo,Stephen J. Galli,Lawrence M. Lichtenstein +8 more
TL;DR: Study of the effect of the human recombinant c-kit receptor ligand stem cell factor (rhSCF) on the release of inflammatory mediators from human skin mast cells and peripheral blood basophils and compared its activity to that of rhIL-3 found it to be less effective in potentiating IgE-mediated LTC4 release.
Journal Article
Murine NK cell cultures: effects of interleukin-2 and interferon on cell growth and cytotoxic reactivity.
Journal ArticleDOI
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.
Hideki Mitsui,Takuma Furitsu,Ann M. Dvorak,Anne Marie Irani,Lawrence B. Schwartz,Naoki Inagaki,Masao Takei,Kimishige Ishizaka,Krisztina M. Zsebo,S Gillis,Teruko Ishizaka +10 more
TL;DR: It was found that mast cells developed by c-kit ligand were immature even after culture for 14 weeks, and could be sensitized with human IgE for anti-IgE-induced release of histamine, prostaglandin D2, and leukotriene C4.
Journal Article
In vivo interleukin 2 administration augments the generation of alloreactive cytolytic T lymphocytes and resident natural killer cells
TL;DR: In vivo administration of highly purified IL 2, either in concert, with or 2 days after, tumor administration resulted in an augmented CTL response as compared to effector cells harvested from untreated, alloimmunized control animals.