S
S Pease
Researcher at Ludwig Institute for Cancer Research
Publications - 3
Citations - 2480
S Pease is an academic researcher from Ludwig Institute for Cancer Research. The author has contributed to research in topics: Embryonic stem cell & Leukemia inhibitory factor. The author has an hindex of 3, co-authored 3 publications receiving 2421 citations.
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Journal ArticleDOI
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
Rachel Williams,D J Hilton,S Pease,Tracy A. Willson,Colin L. Stewart,David P. Gearing,Erwin F. Wagner,D. Metcalf,Nicos A. Nicola,Nicholas M. Gough +9 more
TL;DR: In this paper, a recombinant myeloid leukaemia inhibitory factor (LIF) was used to replace DIA in the maintenance of totipotent ES cell lines that retain the potential to form chimaeric mice.
Journal ArticleDOI
Isolation of embryonic stem (ES) cells in media supplemented with recombinant leukemia inhibitory factor (LIF)
TL;DR: It is demonstrated that feeder cells are not essential for the isolation of pluripotent ES cell lines in the absence ofFeeder cells in culture medium supplemented with recombinant leukemia inhibitory factor (LIF).
Journal ArticleDOI
LIF: a molecule with divergent actions on myeloid leukaemic cells and embryonic stem cells
Nicholas M. Gough,Rachel Williams,D J Hilton,S Pease,Tracy A. Willson,J Stahl,David P. Gearing,Nicos Anthony Nicola,D. Metcalf +8 more
TL;DR: The identification of LIF as a molecule, necessary and sufficient for the maintenance of ES cells in culture, should have a profound impact on the use of these cells for genetic manipulations.