S
Sachin Kumar
Researcher at Indian Institute of Technology Guwahati
Publications - 168
Citations - 2703
Sachin Kumar is an academic researcher from Indian Institute of Technology Guwahati. The author has contributed to research in topics: Virus & Newcastle disease. The author has an hindex of 25, co-authored 143 publications receiving 1959 citations. Previous affiliations of Sachin Kumar include Virginia–Maryland Regional College of Veterinary Medicine & University of Maryland, College Park.
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Journal ArticleDOI
Newcastle disease virus: current status and our understanding
TL;DR: The NDV based recombinant vaccine offers a pertinent choice for the construction of live attenuated vaccine due to its modular nature of transcription, minimum recombination frequency, and lack of DNA phase during replication.
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Aldehyde group driven aggregation-induced enhanced emission in naphthalimides and its application for ultradetection of hydrazine on multiple platforms
TL;DR: In this article, the effect of a single formyl group that can efficiently transform an aggregation caused quenching (ACQ) system into an AIEEgenic system (NIBD) by strengthening the restriction of intramolecular motion (RIM) of rigid aromatic cores is investigated.
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Immunization of chickens with Newcastle disease virus expressing H5 hemagglutinin protects against highly pathogenic H5N1 avian influenza viruses.
Baibaswata Nayak,Subrat N. Rout,Sachin Kumar,Mohammed S. Khalil,Moustafa M.G. Fouda,Lu'ay E. Ahmed,Kenneth C. Earhart,Daniel R. Perez,Peter L. Collins,Siba K. Samal +9 more
TL;DR: The results suggest that these chimeric viruses have potential as safe and effective bivalent vaccines against NDV and HPAIV and will be convenient and affordable, which will be highly beneficial to the poultry industry.
Journal ArticleDOI
Contributions of the Avian Influenza Virus HA, NA, and M2 Surface Proteins to the Induction of Neutralizing Antibodies and Protective Immunity
Baibaswata Nayak,Sachin Kumar,Joshua M. DiNapoli,Anandan Paldurai,Daniel R. Perez,Peter L. Collins,Siba K. Samal +6 more
TL;DR: There was no indication that M2 is immunogenic or protective, and inclusion of NA in addition to HA in a vaccine preparation for chickens may not enhance the high level of protection provided by HA.
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Evaluation of the Newcastle Disease Virus F and HN Proteins in Protective Immunity by Using a Recombinant Avian Paramyxovirus Type 3 Vector in Chickens
TL;DR: In this paper, a reverse-genetics system for recovery of infectious APMV-3 strain from cloned cDNAs was constructed and two recombinant viruses were generated expressing the NDV fusion (F) and hemagglutininin-neuraminidase (HN) proteins, respectively, from added genes.