S
Safa Ben Mimouna
Researcher at University of Monastir
Publications - 10
Citations - 229
Safa Ben Mimouna is an academic researcher from University of Monastir. The author has contributed to research in topics: Offspring & Oxidative stress. The author has an hindex of 8, co-authored 10 publications receiving 168 citations.
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Journal ArticleDOI
Zinc mitigates renal ischemia-reperfusion injury in rats by modulating oxidative stress, endoplasmic reticulum stress, and autophagy.
Najet Hadj Abdallah,Anna Baulies,Ahlem Bouhlel,Mohamed Bejaoui,Mohamed Amine Zaouali,Safa Ben Mimouna,Imed Messaoudi,José C. Fernández-Checa,Carmen García Ruiz,Hassen Ben Abdennebi +9 more
TL;DR: The potential effect of Zn supplementation to modulate ER pathway and autophagic process after I/R is demonstrated and showed that ZnCl2 enhances renal function and reduces cytolysis.
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Protective role of zinc against the toxicity induced by exposure to cadmium during gestation and lactation on testis development.
TL;DR: The results suggest that the toxic effects of Cd observed during development are mediated by the disruption of Zn metabolism, which is established in mothers during pregnancy causing Zn deficiency in fetuses and continues to become more pronounced during lactation.
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Involvement of testicular DAAM1 expression in zinc protection against cadmium-induced male rat reproductive toxicity
Marouane Chemek,Massimo Venditti,Sana Boughamoura,Safa Ben Mimouna,Imed Messaoudi,Sergio Minucci +5 more
TL;DR: The results imply that Zn could prevent Cd‐induced testicular toxicity and sperm quality alteration in adult male rat after gestational and lactational exposure, probably via the restoration of the testicular DAAM1 expression inhibited by Cd.
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Changes of the mRNA Expression Pattern of Zn Transporters: a Probable Mechanism for Cadmium Retention and Zinc Redistribution in the Suckling Rat Tissues
Marouane Chemek,Sana Boughammoura,Safa Ben Mimouna,Lina Chouchene,Mohamed Banni,Imed Messaoudi +5 more
TL;DR: The results imply that the downregulation of ZnT as well as the overexpression of ZIP transporters, in responses to the Zn depletion induced by Cd in the tissues of lactating rat and their offspring, play a major role in Cd accumulation and Zn redistribution in tissues of suckling rat.
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Early-Life Exposure to Cadmium Triggers Distinct Zn-Dependent Protein Expression Patterns and Impairs Brain Development
TL;DR: Results show that exposure to Cd significantly increased the metal accumulation and decreased Zn concentrations in the brain of male pups from Cd-treated mothers, and Interestingly, Zn supplementation provided a total or partial correction of the changes induced by the Cd exposure.