Saikat Das

TL;DR: A simple, highly diastereoselective, Lewis acid catalyzed Friedel-Crafts coupling of a cyclic allylic alcohol with resorcinol derivatives has been developed and achieved with high atom economy, in a protecting group free manner and in less than 6 steps, the longest linear sequence.

TL;DR: Lewis acid catalysed [6+2] cycloaddition reaction for the synthesis of pyrrolo[1,2-a]indoles generating three contiguous stereocenters in a highly regio- and diastereoselective manner has been developed and further applied for the construction of the fully functionalized tricyclic core of yuremamine.

TL;DR: A biomimetic total syntheses of antibacterial natural products (±)-callistrilones A, B, and D, the first triketone-phloroglucinol-monoterpene hybrids with an unprecedentedbenzofuro-xanthene ring system along with the postulated biosynthetic intermediate, isolated from the leaves of Callistemon rigidus, were achieved.

TL;DR: First enantiospecific total syntheses of the cannabinol-skeletal carbazole alkaloids murrayamines-O and -P isolated from root barks of Murraya euchrestifoli, have been accomplished by highly diastereoselective, Lewis acid catalyzed coupling reactions of commercially available monoterpenes withcarbazole derivative, which established the absolute configuration of the natural products.

TL;DR: Ru-catalysed oxidative coupling of allylsilanes and allyl esters with activated olefins has been developed via isomerization followed by C(allyl)–H activation providing efficient access to stereodefined 1,3-dienes in excellent yields.