S
Sampath C. Abeylath
Researcher at University of South Florida
Publications - 4
Citations - 314
Sampath C. Abeylath is an academic researcher from University of South Florida. The author has contributed to research in topics: Emulsion polymerization & Monomer. The author has an hindex of 4, co-authored 4 publications receiving 291 citations.
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Journal ArticleDOI
Penicillin-bound polyacrylate nanoparticles: Restoring the activity of β-lactam antibiotics against MRSA
Edward Turos,G. Suresh Kumar Reddy,Kerriann Greenhalgh,Praveen Ramaraju,Sampath C. Abeylath,Seyoung Jang,Sonja Dickey,Daniel V. Lim +7 more
TL;DR: The preparation of antibacterially active emulsified polyacrylate nanoparticles in which a penicillin antibiotic is covalently conjugated onto the polymeric framework have equipotent in vitro antibacterial properties against methicillin-susceptible and methiillin-resistant forms of Staphylococcus aureus and indefinite stability toward beta-lactamase.
Journal ArticleDOI
Drug delivery approaches to overcome bacterial resistance to beta-lactam antibiotics.
Sampath C. Abeylath,Edward Turos +1 more
TL;DR: Of the progress made so far to develop approaches to overcome bacterial resistance to β-lactams, the use of drug carriers such as liposomes and nanoparticles seems to hold significant promise, as do structural variants that operate through different biological modes of action.
Journal ArticleDOI
Glyconanobiotics: Novel carbohydrated nanoparticle antibiotics for MRSA and Bacillus anthracis.
TL;DR: Overall, the study shows that even relatively large, polar acrylate monomers can be efficiently incorporated into the nanoparticle matrix by emulsion polymerization, providing opportunities for further advances in nanomedicine.
Journal ArticleDOI
Glycosylated polyacrylate nanoparticles by emulsion polymerization.
Sampath C. Abeylath,Edward Turos +1 more
TL;DR: This methodology allows for a new, simple route to the synthesis of polymeric glyconanoparticles with potential applications in targeted drug delivery and materials development.