Showing papers by "Samy M. El-Megharbel published in 2009"

Spectroscopic, thermal and biological studies of coordination compounds of sulfasalazine drug: Mn(II), Hg(II), Cr(III), ZrO(II), VO(II) and Y(III) transition metal complexes

Abstract: The complexations of sulfasalazine (H3Suz) with some of transition metals have been investigated. Three types of complexes, [Mn(HSuz)−2(H2O)4]·2H2O, [M(HSuz)−2(H2O)2]·xH2O (M = Hg(II), ZrO(II) and VO(II), x = 4, 8 and 6, respectively) and [M(HSuz)−2(Cl)(H2O)3]·xH2O (M = Cr(III) and Y(III), x = 5 and 6, respectively) were obtained and characterized by physicochemical and spectroscopic methods. The IR spectra of the complexes suggest that the sulfasalazine behaves as a monoanionic bidentate ligand. The thermal decomposition of the complexes as well as thermodynamic parameters (δE*, δH*, δS* and δG*) were estimated using Coats-Redfern and Horowitz-Metzger equations. In vitro antimicrobial activities of the H3Suz and the complexes were tested.

Infrared and Thermal Analysis of Vanadyl(II) Barbiturate Complex

Abstract: An usual method for the preparation of vanadyl(II) barbiturate complex was performed under the chemical reaction of vanadyl(II) sulfate with barbituric acid (H 2 L) and formulated as: [VO(HL) 2 ].2H 2 O. This new barbiturate complex was synthesis and characterized by elemental analysis, molar conductivity, magnetic measurements, infrared spectral method and simultaneous thermal analysis (TG/DTG) techniques. The molar conductance measurements proved that barbiturate vanadyl(II) complex is non-electrolytes. The infrared spectra of the barbituric and vanadyl(II) complex are used to identify the mode of coordination. Kinetic and thermodynamic parameters ( E *, Δ H *, Δ S * and Δ G *) of H 2 L ligand and its complex are estimated according to the DTG curves.