S
Sandeep
Researcher at Central Institute of Medicinal and Aromatic Plants
Publications - 13
Citations - 191
Sandeep is an academic researcher from Central Institute of Medicinal and Aromatic Plants. The author has contributed to research in topics: Biology & Triterpene. The author has an hindex of 4, co-authored 6 publications receiving 126 citations.
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Journal ArticleDOI
A thaumatin-like protein of Ocimum basilicum confers tolerance to fungal pathogen and abiotic stress in transgenic Arabidopsis
TL;DR: Functional characterization of an Ocimum basilicum PR5 family member (ObTLP1) that was identified from a MeJA-responsive expression sequence tag collection suggests its antifungal activity and might be useful for providing tolerance to the fungal pathogens and abiotic stresses in crops.
Journal ArticleDOI
Two CYP716A subfamily cytochrome P450 monooxygenases of sweet basil play similar but nonredundant roles in ursane- and oleanane-type pentacyclic triterpene biosynthesis
R Misra,Shubha Rani Sharma,Shubha Rani Sharma,Sandeep,Anchal Garg,Chandan S. Chanotiya,Sumit Ghosh,Sumit Ghosh +7 more
TL;DR: The results suggest similar as well as distinct roles of CYP716A252 and CYP 716A253 for the spatio-temporal biosynthesis of PCTs, which might be useful for the alternative and sustainable production of P CTs in microbial host, besides increasing plant metabolite content through genetic modification.
Journal ArticleDOI
Oxidosqualene cyclase and CYP716 enzymes contribute to triterpene structural diversity in the medicinal tree banaba
TL;DR: Combinatorial expression of OSCs and CYP716s in Saccharomyces cerevisiae and Nicotiana benthamiana led to PCT pathway reconstruction, signifying the utility of banaba enzymes for bioactive PCT production in alternate plant/microbial hosts that are more easily tractable than the tree species.
Journal ArticleDOI
Transcriptome analysis and functional characterization of oxidosqualene cyclases of the arjuna triterpene saponin pathway.
TL;DR: A combined transcriptomics, metabolomics and biochemical approach was employed to functionally define a suite of oxidosqualene cyclases (OSCs) that catalyzed key reactions towards triterpene scaffold diversification in arjuna tree bark.
Book ChapterDOI
Triterpenoids: Structural diversity, biosynthetic pathway, and bioactivity
Sandeep,Sumit Ghosh +1 more
TL;DR: Owing to the structural diversity, triterpenoids show an enormous range of bioactivities such as anticarcinogenic, hepatoprotective, antidiabetic, antiinflammatory, antioxidant, and antimicrobial which have significant pharmaceutical and industrial applications.