S
Sandeep Saini
Researcher at Panjab University, Chandigarh
Publications - 6
Citations - 34
Sandeep Saini is an academic researcher from Panjab University, Chandigarh. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 3, co-authored 6 publications receiving 21 citations.
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Journal ArticleDOI
Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity.
Sandeep Saini,Avneet Saini,Chander Jyoti Thakur,Varinder Kumar,Rishabh Dilip Gupta,Jogesh Kumar Sharma +5 more
TL;DR: Gen enrichment tool analysis and substantial literature evidences suggests role of genes like BMPR2 and p53 in pulmonary vasculature and antiviral innate immunity respectively and predicted 26 mature miRNAs from genome of SARS-CoV-2 that targets human genes involved in pathways like EGF receptors signaling, apoptosis signaling, VEGF signaling, FGF receptor signaling.
Journal ArticleDOI
Computational prediction of miRNAs in Nipah virus genome reveals possible interaction with human genes involved in encephalitis.
Sandeep Saini,Chander Jyoti Thakur,Varinder Kumar,Suchita Tandon,Varuni Bhardwaj,Sonia Maggar,Stanzin Namgyal,Gurpreet Kaur +7 more
TL;DR: Predicting significant genes in human that can be inhibited by miRNAs of NiV and results in etiology of encephalitis are reported, which shows their involvement in host defense, blood brain barrier, neurogenesis, mental retardation and encephalopathy.
Posted ContentDOI
Genome Wide Computational Prediction of miRNAs in Kyasanur Forest Disease Virus and their Targeted Genes in Human
TL;DR: The virus genome was scanned for prediction of miRNAs that can inhibit host target genes and all four pre-miRNAs were classified as real.
Journal ArticleDOI
Deciphering the functional role of hypothetical proteins from Chloroflexus aurantiacs J-10-f1 using bioinformatics approach.
Chander Jyoti Thakur,Sandeep Saini,Aayushi Notra,Bhawanshu Chauhan,Sarthak Arya,Rishabh Dilip Gupta,Jyotsna Thakur,Varinder Kumar +7 more
TL;DR: Most of the high confidence-hypothetical proteins of Chloroflexus aurantiacus J-10-f1 were involved in photosynthesis, carbohydrate metabolism, biofuel production and cellulose synthesis processes and few could provide resistance to bacteria at high temperature due to their thermophilic nature.
Journal ArticleDOI
Comparative Analysis of Gene Prediction Tools: RAST, Genmark hmm and AMIgene
TL;DR: Whether the prediction tools and pipeline are providing same or different result for the same genome or not is compared, to find the reason behind the variation in prediction result and try to relate the analysis with nowadays high throughput data analysis.