Showing papers by "Sandra Mary Lima Vasconcelos published in 2019"
TL;DR: The present study presents an update on metabolic pathways that involve redox imbalance and inflammation induced by chronic exposure to hyperglycemia in the pathogenesis of diabetic kidney disease.
Abstract: Chronic hyperglycemia is the key point of macro- and microvascular complications associated with diabetes mellitus. Excess glucose is responsible for inducing redox imbalance and both systemic and intrarenal inflammation, playing a critical role in the pathogenesis of diabetic kidney disease, which is currently the leading cause of dialysis in the world. The pathogenesis of the disease is complex, multifactorial and not fully elucidated; many factors and mechanisms are involved in the development, progression and clinical outcomes of the disease. Despite the disparate mechanisms involved in renal damage related to diabetes mellitus, the metabolic mechanisms involving oxidative/inflammatory pathways are widely accepted. The is clear evidence that a chronic hyperglycemic state triggers oxidative stress and inflammation mediated by altered metabolic pathways in a self-perpetuating cycle, promoting progression of cell injury and of end-stage renal disease. The present study presents an update on metabolic pathways that involve redox imbalance and inflammation induced by chronic exposure to hyperglycemia in the pathogenesis of diabetic kidney disease.
32 citations
Bernardete Weber, Ângela Cristine Bersch-Ferreira, Camila Ragne Torreglosa1, Aline Marcadenti +222 more•Institutions (11)
TL;DR: The BALANCE Program only slightly improved adherence to a healthy diet in patients with established CVD and had no significant effect on the incidence of cardiovascular events or death.
23 citations
TL;DR: Assim, observou-se relacao entre o consumo de alimentos preditores de risco CV com sedentarismo e colesterol elevado, refletindo a necessidade of acoes de educacao nutricional.
Abstract: Resumo O presente artigo teve como objetivo avaliar o consumo de alimentos protetores e preditores de risco cardiovascular (CV) e sua relacao com fatores de risco cardiovascular (FRCV) por hipertensos do estado de Alagoas. Estudo transversal, de base populacional, com 655 adultos, hipertensos, de ambos os sexos, estudados no periodo de 2013 a 2016. O consumo alimentar foi avaliado por um questionario de frequencia alimentar validado com mensuracao convertida em escores e os alimentos foram divididos em tres grupos: I - processados/preditores de risco CV; II - ultraprocessados/maiores preditores de risco CV; III - alimentos in natura ou minimamente processados/protetores de risco CV. Foram tambem analisadas variaveis socioeconomicas, demograficas, bioquimicas, clinicas e antropometricas. Os escores de consumo dos grupos de alimentos I, II e III foram, respectivamente, 0,11; 0,13 e 0,24 (p = 0,001). O consumo de alimentos processados se correlacionou positivamente com o colesterol serico elevado (p = 0,045) e negativamente com a idade (p = 0,001); ja o de alimentos ultraprocessados correlacionou-se com o sedentarismo (p = 0,01). Assim, observou-se relacao entre o consumo de alimentos preditores de risco CV com sedentarismo e colesterol elevado, refletindo a necessidade de acoes de educacao nutricional.
7 citations
TL;DR: It was concluded that the scores method is able to evaluate food patterns and enables associations to be established between anthropometric, biochemical, socioeconomic and clinical variables and the components of the study diet/food grouping to which the individual was exposed.
Abstract: Resumo O presente artigo tem como objetivo revisar de forma sistematizada a literatura relativa a estudos que utilizaram o metodo dos escores proposto por Fornes e colaboradores, em 2002, para avaliar o consumo alimentar e discutir o metodo na perspectiva de avaliacao do padrao alimentar. Foi realizada busca de artigos nas bases de dados Medline, Lilacs e Scielo. Limitou-se a busca aos idiomas ingles, portugues e espanhol e aos artigos publicados de 2002 ate 2016. Os criterios de inclusao foram: estudos que utilizaram o metodo dos escores proposto por Fornes et al. para avaliar o consumo alimentar. Foram encontrados 8.300 artigos na busca inicial. Apos leitura de titulos, resumos e aplicacao de criterios de exclusao, 14 artigos foram selecionados. Os artigos avaliaram o padrao alimentar adotando diferentes grupos e verificaram associacoes com variaveis antropometricas, socioeconomicas e bioquimicas. Concluiu-se que o metodo dos escores constitui uma ferramenta capaz de avaliar os padroes alimentares e que permite verificar associacoes entre variaveis antropometricas, bioquimicas, socioeconomicas e clinica com os componentes da dieta/grupo alimentar investigado aos quais o individuo foi exposto.
1 citations
16 Sep 2019
TL;DR: When compared with adolescent women, pregnant women of advanced age presented a higher frequency of cesarean deliveries in pregnancies of adolescents and elderly women of public health network.
Abstract: Objectives: to compare the adverse perinatal outcomes in pregnancies of adolescents and elderly women of public health network. Methods: a cross-sectional study carried out with pregnant women at the extremes of reproductive age according to the classification of the Brazilian Ministry of Health (adolescents those aged ≤19 years and those who were older than 35 years) and their newborns. Socioeconomic data (income, schooling, occupation and marital status), as well as clinical (diseases), anthropometric (maternal BMI) and perinatal (gender, weight, length, Apgar and gestational age) data were collected, and Poisson regression in hierarchical model was performed, with the results in Ratio of Prevalence (PR) and its respective Confidence Interval at 95% (95% CI). Results: when comparing adolescent and elderly women, 38.7% vs 54.6% (PR=0.71, CI=0.54-0.94, p=0.002) were observed, respectively, cesarean deliveries; 37.8% vs 25.2% (PR=0.83, CI=0.58-1.19, p=0.332) preterm births; 16.6% vs 20.5% (RP=1.07, CI=0.78-1.46, p=0.666) births of small infants for gestational age (SGA); 18.0% vs 15.3% (RP=1.01, CI=0.69-1.47, p=0.948) births of large-for-gestational-age newborns (LGA); 32.2% vs 34.7% (RP=1.08, CI=0.82-1.42, p=0.578), low birth weight infants and 28.5% vs 42.9% (RP=1.18, CI=0.91-1.54, p=0.201) with high birth length. Conclusions: When compared with adolescent women, pregnant women of advanced age presented a higher frequency of cesarean deliveries.
1 citations
29 Apr 2019
TL;DR: Foram realizadas atividades de EAN interativas e ludicas com jogos, expositores e brincadeiras em seis estacoes dispostas no hall do hospital, alem de distribuicao de material educativo as discussed by the authors.
Abstract: Este artigo tem por objetivo relatar as acoes de educacao alimentar e nutricional (EAN) realizadas no HUPAAdurante um evento em comemoracao ao dia mundial da alimentacaocom a tematica central “Pratique uma alimentacao saudavel”. Foram realizadas atividades de EAN interativas e ludicas com jogos, expositores e brincadeiras em seis estacoes dispostas no hall do hospital, alem de distribuicao de material educativo. A experiencia vivenciada revelou uma excelente aceitacao da tematica e metodologia trabalhada, pois as estacoes foram muito visitadas e funcionaram de maneira ininterrupta. Verificou-se que as acoes de EAN trabalhadas tiveram um impacto positivo na promocao da saude.