Sang-We Kim

TL;DR: In this paper, the optimal duration of chemotherapy for advanced non-small-cell lung cancer (NSCLC) patients with stages IIIB to IV was determined in a randomized trial, where patients who had not progressed after two cycles of chemotherapy were randomly assigned to receive either four (arm A) or two (arm B) more cycles of platinum doublet treatment.

TL;DR: SRS followed by chemotherapy did not improve OS in oligo-brain metastases NSCLC patients compared with upfront chemotherapy, and further study with large number of patients should be needed to confirm the use of upfront chemotherapy alone in this subgroup of patients.

TL;DR: In this article, the frequency of K-ras codon 12 point mutations in stomach cancer was investigated using a sensitive polymerase chain reaction (PCR)-based method in 140 samples and correlated the findings with various clinicopathologic characteristics of the patients.

TL;DR: In this article, the effi cacy and safety of continuing gefi tinib combined with chemotherapy versus chemotherapy alone in patients with EGFR-mutation-positive advanced non-small-cell lung cancer (NSCLC) with acquired resistance to fi rst-line gefifi tinib was evaluated.

TL;DR: Given the complete lack of response in the study population, further development of BIW- 8962 has been discontinued and it is hoped that the negative findings of this study will contribute to other investigations of GM2 as a therapeutic target, possibly by combination therapy, and of alternative tumor markers in patients with SCLC.