S
Sanjay Rajagopalan
Researcher at Case Western Reserve University
Publications - 63
Citations - 4463
Sanjay Rajagopalan is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Vascular disease & Mineralocorticoid receptor. The author has an hindex of 34, co-authored 63 publications receiving 4006 citations. Previous affiliations of Sanjay Rajagopalan include University of Michigan & University Hospitals of Cleveland.
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Regional Angiogenesis With Vascular Endothelial Growth Factor in Peripheral Arterial Disease A Phase II Randomized, Double-Blind, Controlled Study of Adenoviral Delivery of Vascular Endothelial Growth Factor 121 in Patients With Disabling Intermittent Claudication
Sanjay Rajagopalan,Emile R. Mohler,Robert J. Lederman,Farrell O. Mendelsohn,Jorge F. Saucedo,Corey K. Goldman,John Blebea,Jennifer Macko,Paul D. Kessler,Henrik S. Rasmussen,Brian H. Annex +10 more
TL;DR: A single unilateral intramuscular administration of AdVEGF121 was not associated with improved exercise performance or quality of life in this study, and this study does not support local delivery of single-dose VEGF121 as a treatment strategy in patients with unilateral PAD.
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Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity
Sanjay Rajagopalan,Emily C. Somers,Robert D. Brook,Christine Kehrer,Dana Pfenninger,Emily E. Lewis,Anjan Chakrabarti,Bruce C. Richardson,Eric A. Shelden,W. Joseph McCune,Mariana J. Kaplan +10 more
TL;DR: Circulating apoptotic ECs are elevated in young women with SLE and strongly correlate with markedly abnormal vascular function and elevated TF levels, suggesting that heightened endothelial apoptosis may represent an important mechanism for development of atherothrombosis in SLE.
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Usefulness of visceral obesity (waist/hip ratio) in predicting vascular endothelial function in healthy overweight adults
TL;DR: Increased abdominal adiposity determined by an increased waist/hip ratio (WHR) is a strong independent predictor of VED even in healthy overweight adults; this is a finding unexplained by alterations in conventional risk factors, systemic inflammation, or the atherogenic lipoprotein pattern.
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Abnormal brachial artery flow-mediated vasodilation in young adults with major depression
Sanjay Rajagopalan,Robert H. Brook,Melvyn Rubenfire,Elaine Pitt,Elizabeth A. Young,Bertram Pitt +5 more
TL;DR: Depressive illness in patients without traditional risk factors for coronary artery disease is associated with striking abnormalities of endothelial function and elevation of circulating markers of atherosclerosis propensity.
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Mineralocorticoid Receptor Antagonism in Experimental Atherosclerosis
TL;DR: MR antagonism improves endothelial function and reduces O2·− generation in diet-induced atherosclerosis and Targeting aldosterone by blocking its receptor has potential antiatherosclerotic effects.