S
Santosh Kumar
Researcher at University of Tennessee Health Science Center
Publications - 277
Citations - 6345
Santosh Kumar is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Population & Oxidative stress. The author has an hindex of 41, co-authored 253 publications receiving 5270 citations. Previous affiliations of Santosh Kumar include University of California, San Diego & University of Montana.
Papers
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Journal ArticleDOI
Amino acid sequence of the regulatory subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase.
Koiti Titani,Tatsuru Sasagawa,Lowell H. Ericsson,Santosh Kumar,Stephen B. Smith,Edwin G. Krebs,Kenneth A. Walsh +6 more
TL;DR: Comparison of the three domains with corresponding regions of the type I isozyme, of the Escherichia coli catabolite gene activator protein, and of cGMP-dependent protein kinase indicates extensive regions of homology and as much as 50% identity with the sequence of an internal segment of the types I and II isozyme.
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Combined sequence and structure analysis of the fungal laccase family
TL;DR: In this article, a set of four ungapped sequence regions, L1-L4, are identified as the overall signature sequences that can be used to identify the laccases, distinguishing them within the broader class of multi-copper oxidases.
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Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase.
Shozo Shoji,David C. Parmelee,Roger D. Wade,Santosh Kumar,Lowell H. Ericsson,Kenneth A. Walsh,Hans Neurath,George L. Long,Jacques G. Demaille,Edmond H. Fischer,Koiti Titani +10 more
TL;DR: The complete amino acid sequence of the 349-residue catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle is presented and predictions of secondary structure suggest the presence of three major domains.
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Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
TL;DR: This review discusses the recent progress towards the use of P450 enzymes in a variety of applications, and expands upon the current progress in P450 engineering approaches describing several recent examples that are utilized to enhance heterologous expression, stability, catalytic efficiency and utilization of alternate oxidants.
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In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation
Jing Jing Li,Bin Wang,Mahesh Chandra Kodali,Chao Chen,Eunhee Kim,Benjamin J. Patters,Lubin Lan,Santosh Kumar,Xinjun Wang,Junming Yue,Francesca-Fang Liao +10 more
TL;DR: The experimental results suggest that circulating exosomes may act as a neuroinflammatory mediator in systemic inflammation.