S
Satoshi Nakago
Researcher at Kobe University
Publications - 22
Citations - 630
Satoshi Nakago is an academic researcher from Kobe University. The author has contributed to research in topics: Population & Leiomyoma. The author has an hindex of 13, co-authored 20 publications receiving 608 citations. Previous affiliations of Satoshi Nakago include John Radcliffe Hospital & University of Oxford.
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Journal ArticleDOI
Effects of 3,5,3'-triiodothyronine on the invasive potential and the expression of integrins and matrix metalloproteinases in cultured early placental extravillous trophoblasts.
Noriyoshi Oki,Hiroya Matsuo,Satoshi Nakago,Homare Murakoshi,Jovelle B. Laoag-Fernandez,Takeshi Maruo +5 more
TL;DR: The present results suggest that T(3) (10(-8) m) may play a vital role in up-regulating the invasive potential of EVTs into the decidua.
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Effects of progesterone on growth factor expression in human uterine leiomyoma.
Takeshi Maruo,Hiroya Matsuo,Yosuke Shimomura,Osamu Kurachi,Zhijian Gao,Satoshi Nakago,Takeshi Yamada,Wei Chen,Jiayin Wang +8 more
TL;DR: The results obtained suggest that P4 has dual actions on uterine leiomyoma growth: one is to stimulate le iomyoma cell growth and survival through up-regulating EGF and Bcl-2 protein expression as well as down- Regulating TNFalpha expression in those cells, and the other is to inhibit leiomersic cell growth through down-Regulating IGF-I expression inThose cells.
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Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 protein expression in human uterine leiomyoma cells
TL;DR: The present results suggest that IGF-I plays crucial roles in leiomyoma cell growth, not only in promoting the proliferative potential by up-regulation of PCNA expression but also in down-regulating apoptosis by up -regulation of Bcl-2 protein expression in leoomyoma cells.
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The tumor necrosis factor-alpha promoter -1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population.
Tasneem Asghar,Shigeki Yoshida,Stephen Kennedy,Kenichi Negoro,Wang Zhuo,Shinya Hamana,Satoru Motoyama,Satoshi Nakago,David H. Barlow,Takeshi Maruo +9 more
TL;DR: The variability of the -1031T/C polymorphism of the TNF-alpha gene may be associated with susceptibility to endometriosis.
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Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population
Satoshi Nakago,Ruth M. Hadfield,Krina T. Zondervan,Helen J. Mardon,Sanjiv Manek,Daniel E. Weeks,David H. Barlow,Stephen Kennedy +7 more
TL;DR: The relationship between endometriosis and polymorphisms in the N-acetyl transferase 2 (NAT 2) gene was investigated in a UK population, and data suggest that altered NAT 2 enzyme activity may be a predisposition factor in endometRIosis, or that NAT 2 alleles may be in linkage disequilibrium with a susceptibility allele in the same chromosomal region.