Schutt Aj

TL;DR: One‐hundred‐ninety‐four eligible and evaluable patients with histologically confirmed locally unresectable adenocarcinoma of the pancreas were randomly assigned to therapy with high‐dose radiation therapy alone, to moderate‐dose (4000 rads) radiation + 5‐fluorouracil (5‐FU), and to high‐ dose radiation plus 5‐FU.

TL;DR: In a controlled double blind study involving 116 patients with far‐advanced gastrointestinal cancer, dexamethasone at dosages of 0.75 and 1.5 mg four times daily produced improved appetite and sense of well‐being in comparison to placebo treatment, however, it was not accompanied by weight gain or improved performance status.

TL;DR: In a randomized, controlled study of 80 patients with advanced colorectal carcinoma, the combination of 5-fluorouracil, methyl-1, 3-cis(2-chlorethyl)-1-nitrosourea, and vincristine produced an overall degree to toxicity comparable to that of5-FU used alone.

TL;DR: The median survival of patients who received adriamycin as initial treatment was 12 weeks compared to 8 weeks for methotrexate and 6 weeks for actinomycin‐D therapy, and the duration of responses ranged from 43–64 days for those patients with no chemotherapy prior to study entry.