S
Sengottuvelan Balasubramanian
Researcher at University of Madras
Publications - 53
Citations - 786
Sengottuvelan Balasubramanian is an academic researcher from University of Madras. The author has contributed to research in topics: PLGA & Ring (chemistry). The author has an hindex of 14, co-authored 53 publications receiving 636 citations. Previous affiliations of Sengottuvelan Balasubramanian include Center for Advanced Materials.
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Synthesis, characterization and electrochemistry of 4′-functionalized 2,2′:6′,2″-terpyridine ruthenium(II) complexes and their biological activity
TL;DR: A biological study of the complexes indicated that the complexes exhibit very good activity against most of the test pathogens and their activity is better than those of some of the commercially available antibiotics like tetracycline and the fungicide carbendazim.
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One pot green synthesis of Ag, Au and Au-Ag alloy nanoparticles using isonicotinic acid hydrazide and starch.
TL;DR: The catalytic behavior of alloy nanoparticles indicate that the rate constant for the reduction of 4-nitro phenol to 4-amino phenol increases exponentially from metallic Ag to metallic Au as Au content increases in the Au-Ag Alloy nanoparticles.
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Novel PLGA-based nanoparticles for the oral delivery of insulin.
Sampath Malathi,Perumal Nandhakumar,Velayudham Pandiyan,Thomas J. Webster,Sengottuvelan Balasubramanian +4 more
TL;DR: Histopathological studies reveal that ISTPPLG6 NPs could restore the damage caused by streptozotocin in the liver, kidneys, and pancreas, indicating its biocompatibility and regenerative effects.
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Gold nanoparticle conjugated PLGA-PEG-SA-PEG-PLGA multiblock copolymer nanoparticles: synthesis, characterization, in vivo release of rifampicin.
Mani Gajendiran,Sheik Mohammed Jainuddin Yousuf,Vellaichamy Elangovan,Sengottuvelan Balasubramanian +3 more
TL;DR: In vivo drug release studies in male Wistar rats show that AuNP conjugated multiblock copolymer NPs exhibit drug release up to 240 h and the nanoconjugates exhibit 18.13-29.41 μg mL-1 of Cmax with a delayed Tmax and the relative bioavailability is increased to 107-190.
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Isoniazid loaded core shell nanoparticles derived from PLGA-PEG-PLGA tri-block copolymers: in vitro and in vivo drug release.
Mani Gajendiran,Venkatachalam Gopi,Vellaichamy Elangovan,Rajagopalan Venkatakrishna Murali,Sengottuvelan Balasubramanian +4 more
TL;DR: The pharmacokinetic studies show that the INH bioavailability of INH loaded CSNPs is 28 fold higher than that of free INH and also theCSNPs show sustained drug release for longer duration.