S
Serdar Coskun
Researcher at Alfaisal University
Publications - 83
Citations - 2687
Serdar Coskun is an academic researcher from Alfaisal University. The author has contributed to research in topics: Preimplantation genetic diagnosis & Oocyte. The author has an hindex of 26, co-authored 80 publications receiving 2340 citations. Previous affiliations of Serdar Coskun include Ohio State University.
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Journal ArticleDOI
Day 5 versus day 3 embryo transfer: a controlled randomized trial
Serdar Coskun,J. M. G. Hollanders,Saad Al-Hassan,Hamad Al-Sufyan,Hend Al-Mayman,Kamal Jaroudi +5 more
TL;DR: Day 3 and 5 transfer had similar pregnancy, implantation and twinning rates and currently, day 5 transfers have no advantages over day 3 transfers.
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The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome
TL;DR: There is a positive linear relationship between the endometrial thickness measured on the day of hCG injection and PR, and is independent of other variables, and hence aiming for a thicker endometrium should be considered.
Journal ArticleDOI
TLE6 mutation causes the earliest known human embryonic lethality
Anas M. Alazami,Salma Awad,Serdar Coskun,Saad Al-Hassan,Hadia Hijazi,Firdous Abdulwahab,Coralie Poizat,Fowzan S. Alkuraya +7 more
TL;DR: It is shown that the TLE6 mutation is gender-specific and leads to the earliest known human embryonic lethality phenotype, in this first report of a human defect in a member of the subcortical maternal subcritical maternal complex.
Journal ArticleDOI
Multiple displacement amplification on single cell and possible PGD applications
Ali Hellani,Serdar Coskun,Moncef Benkhalifa,Abelghani Tbakhi,Nadia Sakati,Ali Al-Odaib,Pinar Ozand +6 more
TL;DR: The amplification accuracy of MDA permitted the detection of trisomy 21 on a single cell using comparative genome hybridization-array and suggest that MDA can be used for single cell molecular karyotyping and the diagnosis of any single gene disorder in PGD.
Journal ArticleDOI
Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro
Senthilkumar A. Natesan,Alex J. Bladon,Serdar Coskun,Wafa Qubbaj,R. Prates,Santiago Munné,Edith Coonen,Joseph C F M Dreesen,Servi J. C. Stevens,Aimee D C Paulussen,Sharyn Stock-Myer,Leeanda Wilton,Souraya Jaroudi,Dagan Wells,Anthony P.C. Brown,Alan H. Handyside +15 more
TL;DR: Genome-wide karyomapping is highly accurate and facilitates analysis of the inheritance of almost any single-gene defect, or any combination of loci, at the single-cell level, greatly expanding the range of conditions for which preimplantation genetic diagnosis can be offered clinically without the need for customized test development.