Serge Pauillac

TL;DR: Cytotoxic effects associated with sodium channel activation were evaluated for the two classes of toxins on murine neuroblastoma cells, and their acute toxicity was determined in mice, suggesting that the high toxicity of CTXs is related to sodium-dependent disturbances of the excitable membranes but might also involve other cellular mechanisms.

TL;DR: The results suggest the usefulness of the D8–D10 portion of the Gambierdiscus LSU rDNA as a valuable taxonomic marker and consistency between species designations based on SEM microscopy and classification inferred from biochemical and genetic heterogeneities was examined.

TL;DR: Toxin composition comparison between two G. polynesiensis strains suggests that the toxin profile is a stable characteristic in this species, which proved inherently more toxic than other Gambierdiscus species isolated from other geographical areas.

TL;DR: This review aims to describe the methodologies available for CTX detection, including those based on the toxicological, biochemical, chemical, and pharmaceutical properties of CTXs, and to study the onset of CFP in Europe.

TL;DR: The findings suggest that, locally, the traditional knowledge about ciguatera may not be scientifically complete but is functionally correct, and community education resulted in self-regulating behaviour towards avoidance of high-risk fish species and fishing locations.