S
Sergio Li Calzi
Researcher at Cedars-Sinai Medical Center
Publications - 2
Citations - 660
Sergio Li Calzi is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Downregulation and upregulation & Separase. The author has an hindex of 2, co-authored 2 publications receiving 635 citations.
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Journal ArticleDOI
Glucagon-Like Peptide 1 Inhibits Cell Apoptosis and Improves Glucose Responsiveness of Freshly Isolated Human Islets
Loredana Farilla,Loredana Farilla,Angela Bulotta,Boaz Hirshberg,Sergio Li Calzi,Nasif Khoury,Houtan Noushmehr,Cristina Bertolotto,Cristina Bertolotto,Umberto Di Mario,David M. Harlan,Riccardo Perfetti,Riccardo Perfetti +12 more
TL;DR: Evidence is provided that GLP-1 added to freshly isolated human islets preserves morphology and function and inhibits cell apoptosis, and better-preserved three-dimensional islet morphology in the GLp-1-treated islets, compared with controls.
Journal ArticleDOI
Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.
TL;DR: Results show that mPT TG exhibits properties consistent with a murine securin in insulin-secreting mouse cells and mPTTG overexpression inhibits cell proliferation, suggesting that defective beta-cell proliferation observed in PTTG-/- mice is likely due to abnormal cell-cycle progression.