S
Sergio López-Briones
Researcher at Universidad de Guanajuato
Publications - 26
Citations - 772
Sergio López-Briones is an academic researcher from Universidad de Guanajuato. The author has contributed to research in topics: Immune system & Peripheral blood mononuclear cell. The author has an hindex of 11, co-authored 25 publications receiving 657 citations. Previous affiliations of Sergio López-Briones include National Autonomous University of Mexico & Johns Hopkins University.
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Journal ArticleDOI
Phenotypic and Functional Characterization of Kidney-Infiltrating Lymphocytes in Renal Ischemia Reperfusion Injury
Dolores Ascon,Sergio López-Briones,Manchang Liu,Miguel Ascon,Vladimir Savransky,Robert B. Colvin,Mark J. Soloski,Hamid Rabb +7 more
TL;DR: Analyzing the lymphocyte populations infiltrating into mouse kidneys 3 and 24 h after renal IRI provides mechanistic insight into how lymphocytes modulate IRI, as well as demonstrating that abdominal surgery alone leads to lymphocyte changes in kidney.
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A novel role of the lumican core protein in bacterial lipopolysaccharide-induced innate immune response.
TL;DR: It is shown that bacterial lipopolysaccharide sensing by the Toll-like receptor 4 signaling pathway and innate immune response is regulated by lumican, and an exogenous recombinant lumican core protein increases lipopoly Saccharide-mediated TNFα induction and partially rescues innateimmune response in Lum-/- macrophages.
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A PPARγ, NF-κB and AMPK-Dependent Mechanism May Be Involved in the Beneficial Effects of Curcumin in the Diabetic db/db Mice Liver
Lizbeth M Jiménez-Flores,Sergio López-Briones,Maciste H. Macías-Cervantes,Joel Ramírez-Emiliano,Victoriano Pérez-Vázquez +4 more
TL;DR: Curcumin regulates the expression of AMPK, PPARγ, and NF-κB; suggesting a beneficial effect for treatment of T2DM complications.
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Normal mouse kidneys contain activated and CD3+CD4−CD8− double-negative T lymphocytes with a distinct TCR repertoire
Dolores Ascon,Miguel Ascon,Shailesh R. Satpute,Sergio López-Briones,Lorraine C. Racusen,Robert B. Colvin,Mark J. Soloski,Hamid Rabb +7 more
TL;DR: The data suggest that some of these cells harbored in the kidney could be implicated in the immune response of the IRI pathogenic process.
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Effects of curcumin on brain-derived neurotrophic factor levels and oxidative damage in obesity and diabetes
Elena Franco-Robles,Alejandra Campos-Cervantes,Blanca Murillo-Ortiz,José Segovia,Sergio López-Briones,Paula Vergara,Victoriano Pérez-Vázquez,Martha Silvia Solís-Ortiz,Joel Ramírez-Emiliano +8 more
TL;DR: A therapeutic potential of curcumin is suggested to decrease oxidation caused by obesity in humans and also show thatCurcumin restores BDNF levels in DM and in sera of obese humans.