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Seung Chul Shin
Researcher at Yonsei University
Publications - 3
Citations - 2091
Seung Chul Shin is an academic researcher from Yonsei University. The author has contributed to research in topics: Microbiome & Innate immune system. The author has an hindex of 3, co-authored 3 publications receiving 1899 citations. Previous affiliations of Seung Chul Shin include Ewha Womans University & Seoul National University.
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Journal ArticleDOI
Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila.
Ji-Hwan Ryu,Sung-Hee Kim,Hyo-Young Lee,Hyo-Young Lee,Jin Young Bai,Young-Do Nam,Jin-Woo Bae,Dong Gun Lee,Seung Chul Shin,Seung Chul Shin,Eun-Mi Ha,Won-Jae Lee +11 more
TL;DR: It is shown that the intestinal homeobox gene Caudal regulates the commensal-gut mutualism by repressing nuclear factor kappa B–dependent antimicrobial peptide genes, and reveals that a specific genetic deficiency within a host can profoundly influence the gut commensAL microbial community and host physiology.
Journal ArticleDOI
Drosophila Microbiome Modulates Host Developmental and Metabolic Homeostasis via Insulin Signaling
Seung Chul Shin,Seung Chul Shin,Sung-Hee Kim,Hyejin You,Hyejin You,Bo-Ram Kim,Bo-Ram Kim,Aeri C. Kim,Aeri C. Kim,Kyung-Ah Lee,Joo-Heon Yoon,Ji-Hwan Ryu,Won-Jae Lee +12 more
TL;DR: It is shown that the pyrroloquinoline quinone–dependent alcohol dehydrogenase activity of a commensal bacterium, Acetobacter pomorum, modulates insulin/insulin-like growth factor signaling in Drosophila to regulate host homeostatic programs controlling developmental rate, body size, energy metabolism, and intestinal stem cell activity.
Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling
Seung Chul Shin,Seung Chul Shin,Sung-Hee Kim,Hyejin You,Hyejin You,Bo-Ram Kim,Bo-Ram Kim,Aeri C. Kim,Aeri C. Kim,Kyung-Ah Lee,Joo-Heon Yoon,Ji-Hwan Ryu,Won-Jae Lee +12 more
TL;DR: In this article, the pyrroloquinoline quinone-dependent alcohol dehydrogenase (PQQ-ADH) activity of a commensal bacterium, Acetobacter pomorum, modulates insulin/insulin-like growth factor signaling (IIS) in Drosophila to regulate host homeostatic programs controlling developmental rate, body size, energy metabolism, and intestinal stem cell activity.