S
SH Kirk
Researcher at Nottingham Trent University
Publications - 13
Citations - 472
SH Kirk is an academic researcher from Nottingham Trent University. The author has contributed to research in topics: DNA damage & DNA repair. The author has an hindex of 9, co-authored 13 publications receiving 435 citations.
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Thymine metabolism and thymineless death in prokaryotes and eukaryotes
TL;DR: A model is presented for a molecular basis of TLD and suggests that the RecF repair pathway may be critical to cell death, perhaps because it increases the occurrence of double-strand DNA breaks with unique DNA configurations at lesion sites.
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Near-ultraviolet photolysis of β-phenylpyruvic acid generates free radicals and results in DNA damage
TL;DR: Evidence is presented that photolysis of beta-phenylpyruvic acid by a skin tanning lamp, emitting 99% UVA and 1% UVB generates carboxyl radicals (CO(2)(*)) and also possibly causes direct electron transfer reactions, lending importance to photolytic studies of this agent.
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Amniotic membrane collagen content and type distribution in women with preterm premature rupture of the membranes in pregnancy
TL;DR: PPROM is accompanied by generalised reduction in amnion collagen content, involving all fibrillar sub‐types monitored, and may reflect general changes in protease activity or in collagen expression in affected membranes.
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Molecular biology of Fanconi anaemia--an old problem, a new insight.
TL;DR: Molecular analysis of the FANC proteins will provide vital information on normal cell responses to damage and allow therapeutic strategies to be developed that will hopefully supplant bone marrow transplantation.
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Localization of Monoamine Oxidase mRNA in Human Placenta
TL;DR: The first demonstration of the cellular distribution of MAO mRNA in human placenta via in situ hybridization is demonstrated and these highly specific cRNA probes can now be used to study the distribution ofMAO-A and MAO-B expression in other tissues.