Hydrogels for biomedical applications.

In the present review, we focused on the fundamental concepts of hydrogels-classification, the polymers involved, synthesis methods, types of hydrogels, properties, and applications of the hydrogel. Hydrogels can be synthesized from natural polymers, synthetic polymers, polymerizable synthetic monomers, and a combination of natural and synthetic polymers. Synthesis of hydrogels involves physical, chemical, and hybrid bonding. The bonding is formed via different routes, such as solution casting, solution mixing, bulk polymerization, free radical mechanism, radiation method, and interpenetrating network formation. The synthesized hydrogels have significant properties, such as mechanical strength, biocompatibility, biodegradability, swellability, and stimuli sensitivity. These properties are substantial for electrochemical and biomedical applications. Furthermore, this review emphasizes flexible and self-healable hydrogels as electrolytes for energy storage and energy conversion applications. Insufficient adhesiveness (less interfacial interaction) between electrodes and electrolytes and mechanical strength pose serious challenges, such as delamination of the supercapacitors, batteries, and solar cells. Owing to smart and aqueous hydrogels, robust mechanical strength, adhesiveness, stretchability, strain sensitivity, and self-healability are the critical factors that can identify the reliability and robustness of the energy storage and conversion devices. These devices are highly efficient and convenient for smart, light-weight, foldable electronics and modern pollution-free transportation in the current decade.

Fundamental Concepts of Hydrogels: Synthesis, Properties, and Their Applications

Physically cross-linked chitosan-based hydrogels for tissue engineering applications: A state-of-the-art review

The versatility of collagen and chitosan: From food to biomedical applications

A plethora of applications using polysaccharides have been developed in recent years due to their availability as well as their frequent nontoxicity and biodegradability. These polymers are usually obtained from renewable sources or are byproducts of industrial processes, thus, their use is collaborative in waste management and shows promise for an enhanced sustainable circular economy. Regarding the development of novel delivery systems for biotherapeutics, the potential of polysaccharides is attractive for the previously mentioned properties and also for the possibility of chemical modification of their structures, their ability to form matrixes of diverse architectures and mechanical properties, as well as for their ability to maintain bioactivity following incorporation of the biomolecules into the matrix. Biotherapeutics, such as proteins, growth factors, gene vectors, enzymes, hormones, DNA/RNA, and antibodies are currently in use as major therapeutics in a wide range of pathologies. In the present review, we summarize recent progress in the development of polysaccharide-based hydrogels of diverse nature, alone or in combination with other polymers or drug delivery systems, which have been implemented in the delivery of biotherapeutics in the pharmaceutical and biomedical fields.

Recent Progress on Polysaccharide-Based Hydrogels for Controlled Delivery of Therapeutic Biomolecules.

A review on biomacromolecular hydrogel classification and its applications.

Dynamic imine bond based chitosan smart hydrogel with magnified mechanical strength for controlled drug delivery

CMC studies of CTAB, SLS & tween 80 by spectral and conductivity methodology to explore its potential in photogalvanic cell

Comparison of dye (oxazine and thiazine) materials as a photosensitizer for use in photogalvanic cells based on molecular interaction with sodium dodecyl sulphate by spectral study

The photogalvanic cells are rechargeable device with the sun light in which surfactant solutions are potentially important for efficient energy conversion and storage. Here, effect of cationic cetyltrimethyl ammonium bromide (CTAB), anionic sodium dodecyl sulphate (SDS) and non ionic tween 80 surfactants on the electrical output of the cationic oxazine dye brilliant cresyl blue (BCB)-fructose (redox couple) system in photogalvanic cells have been studied. For this, the photopotential and photocurrent for different cells having BCB-fructose system without and with surfactant (CTAB, SDS and tween 80) in the alkaline medium have been measured. The total 30 different cells have been prepared for optimizing the concentration of electrolytes corresponding to the higher electrical out put. Generally, the electrical output increases in presence of a particular surfactant, due to increase in solubilization and stabilization properties of dye molecules in the water. The amount of enhancement in electrical output of BCB-fructose system was highest with SDS and lowest with tween 80, i.e. the order for BCB-fructose system with different surfactants in photogalvanic cells is: BCB-fructose-SDS > BCB-fructose-CTAB > BCB-fructose-tween 80. This order for electrical output was good agreement with the stability order of BCB-SDS/CTAB/tween 80 system, on the basis of spectrophotometric study. Hence, among these surfactants, SDS has stronger capacity, (due to opposite charge on BCB and SDS) to stabilize the BCB-fructose system leads to enhancement in electrical output of photogalvanic cells. Therefore, dye and surfactant, having chemical structure, like BCB and SDS, has a great importance of improvement of electrical performance to photogalvanic cells in the future.

Shachi Tiwari

Papers

A review on biomacromolecular hydrogel classification and its applications.

Dynamic imine bond based chitosan smart hydrogel with magnified mechanical strength for controlled drug delivery

CMC studies of CTAB, SLS & tween 80 by spectral and conductivity methodology to explore its potential in photogalvanic cell

Comparison of dye (oxazine and thiazine) materials as a photosensitizer for use in photogalvanic cells based on molecular interaction with sodium dodecyl sulphate by spectral study

Correlation between Photoelectrochemical and Spectrophotometric Study of Dye-Surfactant Combination in Photogalvanic Cell