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Shao-Ming Lu

Researcher at State University of New York System

Publications -  7
Citations -  807

Shao-Ming Lu is an academic researcher from State University of New York System. The author has contributed to research in topics: Tonic (physiology) & Electrophysiology. The author has an hindex of 7, co-authored 7 publications receiving 787 citations. Previous affiliations of Shao-Ming Lu include Stony Brook University.

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Journal ArticleDOI

Effects of membrane voltage on receptive field properties of lateral geniculate neurons in the cat: contributions of the low-threshold Ca2+ conductance

TL;DR: The contribution of the LT spike on the transmission of visually evoked signals through geniculate relay cells to visual cortex and the effects of membrane voltage, and thus the presence or absence of LT spikes, on responses to drifting sine-wave gratings are studied.
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N-methyl-D-aspartate receptors contribute to excitatory postsynaptic potentials of cat lateral geniculate neurons recorded in thalamic slices.

TL;DR: The voltage and frequency dependence of the NMDA receptor-mediated component of the EPSPs, as well as its ability to trigger low-threshold calcium spikes, provide for complex signal processing in the lateral geniculate nucleus.
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Receiver operating characteristic (ROC) analysis of neurons in the cat's lateral geniculate nucleus during tonic and burst response mode

TL;DR: It is found that the more often a cell responded in burst mode, the larger its ROC area, and this was true for responses to optimal and nonoptimal visual stimuli, the latter including nonOptimal spatial frequencies and low stimulus contrasts.
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Relative contributions of burst and tonic responses to the receptive field properties of lateral geniculate neurons in the cat.

TL;DR: The goal was to study the differential contributions to these visual responses of bursting caused by voltage dependent, low-threshold (LT) Ca2+ spikes and of purely tonic responses unrelated to LT spikes.
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The brain-stem parabrachial region controls mode of response to visual stimulation of neurons in the cat's lateral geniculate nucleus.

TL;DR: During the authors' intracellular recordings of geniculate cells, it was found that, at initially hyperpolarized membrane potentials, LT spiking in response to visual stimulation was pronounced, but that parabrachial activation abolished thisLT spiking and associated burst discharges and led to a progressive increase in tonic responsiveness.