S
Sharafudeen Dahiru Abubakar
Researcher at Ahmadu Bello University
Publications - 18
Citations - 207
Sharafudeen Dahiru Abubakar is an academic researcher from Ahmadu Bello University. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 3, co-authored 13 publications receiving 27 citations. Previous affiliations of Sharafudeen Dahiru Abubakar include Tokyo University of Science & Uthman dan Fodiyo University.
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Journal ArticleDOI
Coronavirus disease 2019 (COVID-19): An overview of the immunopathology, serological diagnosis and management.
Abubakar Umar Anka,Mohammed Ibrahim Tahir,Sharafudeen Dahiru Abubakar,Mohamed Alsabbagh,Zeineb Zian,Haleh Hamedifar,Araz Sabzevari,Gholamreza Azizi +7 more
TL;DR: Treatment approaches to COVID‐19 treatment involve the use of antiviral agents that interfere with the SARS‐CoV‐2 lifecycle to prevent further viral replication and utilizing immunomodulators to dampen the immune system in order to prevent cytokine storm and tissue damage.
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Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment
Stella Amarachi Ihim,Sharafudeen Dahiru Abubakar,Zeineb Zian,Takanori Sasaki,Mohammad Saffarioun,Shayan Maleknia,Gholamreza Azizi +6 more
TL;DR: Combination drug therapies, that focus on IL-18 inhibition, in addition to other cytokines, are highly recommended to be considered as an important area of research that needs to be explored.
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Understanding the Implications of SARS-CoV-2 Re-infections on Immune Response Milieu, Laboratory Tests and Control Measures against COVID-19
Jelili Olaide Mustapha,Idris Nasir Abdullahi,Odunayo O.R. Ajagbe,Anthony Uchenna Emeribe,Samuel Ayobami Fasogbon,Solomon Oloche Onoja,Charles Egede Ugwu,Chikodi Modesta Umeozuru,Folake Olubunmi Ajayi,Wudi Natasha Tanko,Pius Omoruyi Omosigho,Abdulmumuni Samuel Aliyu,Halima Ali Shuwa,Justin Onyebuchi Nwofe,Amos Dangana,Ovye Engom Godiya Alaba,Peter Elisha Ghamba,Yakubu Kokori Enevene Ibrahim,Dorcas Aliyu,Olawale Sunday Animasaun,Nkechi Blessing Ugboaja,Mala Alhaji Baba Mallam,Sharafudeen Dahiru Abubakar,Maijidda Saidu Aminu,Hadiza Yahaya,Silifat Oyewusi +25 more
TL;DR: In this article, a detailed biology of SARS-CoV-2 re-infections and their implications on immune response milieu, diagnostic laboratory tests and control measures against COVID-19 are presented.
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Immunological and Anti-oxidant Profiles of Malarial Children in Abuja, Nigeria
Idris Nasir Abdullahi,Sanusi Musa,Anthony Uchenna Emeribe,Musa Muhammed,Jelili Olaide Mustapha,Halima Ali Shuwa,Shamsuddeen Haruna,Sharafudeen Dahiru Abubakar,Olusoji Matthew Adeyemi Billyrose,Mustapha Bakare +9 more
TL;DR: Severe malaria was significantly associated with declined CD4+ and CD8+ T cell counts, upregulation of IL-6, and high serum levels of oxidative stress biomarkers.
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The role of TNF-α and anti-TNF-α agents in the immunopathogenesis and management of immune dysregulation in primary immunodeficiency diseases
Sharafudeen Dahiru Abubakar,Stella Amarachi Ihim,Amir Farshchi,Shayan Maleknia,Hamisu Abdullahi,Takanori Sasaki,Gholamreza Azizi +6 more
TL;DR: Critical evaluation of the mAbs targeting TNF-α in various immune-mediated complications in PID diseases will be provided, and their clinical efficacy and safety will be reported.