S
Sharon S.Y. Leung
Researcher at The Chinese University of Hong Kong
Publications - 58
Citations - 1849
Sharon S.Y. Leung is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Medicine & Slug flow. The author has an hindex of 20, co-authored 51 publications receiving 1282 citations. Previous affiliations of Sharon S.Y. Leung include Hong Kong University of Science and Technology & University of Sydney.
Papers
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Journal ArticleDOI
Inhaled formulations and pulmonary drug delivery systems for respiratory infections
Qi Tony Zhou,Sharon S.Y. Leung,Patricia Tang,Thaigarajan Parumasivam,Zhi Hui Loh,Hak-Kim Chan +5 more
TL;DR: In view of the fact that no new antibiotic entities against multi-drug resistant bacteria have come close to commercialisation, advanced formulation strategies are in high demand for combating respiratory 'super bugs'.
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Emerging inhalation aerosol devices and strategies: where are we headed?
TL;DR: Recently vibrating-mesh and software technologies have resulted in nebulisers that have remarkably accurate dosing and portability and dry powder inhalers have become highly favourable for delivering high-dose and single-dose drugs with the aid of advanced particle engineering.
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Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections.
Sharon S.Y. Leung,Thaigarajan Parumasivam,Fiona G. Gao,Nicholas B. Carrigy,Reinhard Vehring,Warren H. Finlay,Sandra Morales,Warwick J. Britton,Elizabeth Kutter,Hak-Kim Chan +9 more
TL;DR: Overall, the SD method caused less phage reduction during the powder formation process and the resulted powders achieved better aerosol performance for PEV2.
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Hydrodynamics of liquid–liquid Taylor flow in microchannels
Raghvendra Gupta,Raghvendra Gupta,Sharon S.Y. Leung,Rogerio Manica,David Fletcher,Brian S. Haynes +5 more
TL;DR: In this paper, the hydrodynamics of vertically upward flow of Taylor droplets of water dispersed in a continuous hexadecane phase in a channel of diameter 1.06mm were studied.
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Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders.
Sharon S.Y. Leung,Thaigarajan Parumasivam,Fiona G. Gao,Elizabeth A. Carter,Nicholas B. Carrigy,Reinhard Vehring,Warren H. Finlay,Sandra Morales,Warwick J. Britton,Elizabeth Kutter,Hak-Kim Chan +10 more
TL;DR: It is demonstrated that spray drying is a suitable method to produce stable phage powders for pulmonary delivery and a powder matrix containing ≥40% trehalose provided good phage preservation and aerosol performances after storage at 0 and 22% RH at 4°C for 12 months.