Sharon Varghese

TL;DR: A summary of flavonoids and their effectiveness in cancer treatment targeting apoptosis has been discussed and their high bioavailability, safety, minimal side effects and cost effectiveness are discussed.

TL;DR: The three main metabolic disturbances that occur in diabetes are linked to potential aberrant molecular pathways that may lead to the development of an oncogenic phenotype of the breast tissue, thereby leading to acceleration of cell growth, proliferation, migration, inflammation, angiogenesis, EMT and metastasis and inhibition of apoptosis in breast cancer cells.

TL;DR: This review summarizes the major pathways by which chili contributes to ameliorating parameters that help weight management and how the consumption of chili can help in accelerating weight loss through dietary modifications.

TL;DR: The data indicates that meetingformin in combination with agents that inhibit the glycolytic pathway should be more beneficial for the treatment of triple-negative breast cancers in diabetic individuals, and that metformin treatment was most effective under zero glucose/glucose-starved conditions in MDA-MB-468.

TL;DR: An important role of calcium signaling in the response of neuroblastoma cells to chemotherapy is confirmed and [Ca2+]i modulation as a promising strategy for adjunctive treatment is suggested.