Shaun M. Eack

TL;DR: Positive and negative symptoms were more strongly related to poor QoL among studies of schizophrenia outpatients, whereas general psychopathology showed a consistent negative relationship withQoL across all study samples and treatment settings.

TL;DR: Cognitive enhancement therapy may offer neurobiologic protective and enhancing effects in early schizophrenia that are associated with improved long-term cognitive outcomes and mediated the beneficial cognitive effects of cognitive enhancement therapy.

TL;DR: The two-year effects of an integrated neurocognitive and social-cognitive rehabilitation program, cognitive enhancement therapy (CET), on cognitive and functional outcomes in early course schizophrenia are examined.

TL;DR: It is demonstrated that a connectivity breakdown between the cerebellum and the right dorsolateral prefrontal cortex is associated with negative symptom severity and that correction of this breakdown amelioratesnegative symptom severity, supporting a novel network hypothesis for medication-refractory negative symptoms and suggesting that network manipulation may establish causal relationships between network markers and clinical phenomena.

TL;DR: There is substantial need for the rigorous development and evaluation of psychosocial treatments for adults with ASD, although the quantity and quality of studies is limited.