S
Sheng Qi
Researcher at University of East Anglia
Publications - 89
Citations - 2499
Sheng Qi is an academic researcher from University of East Anglia. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 26, co-authored 77 publications receiving 1922 citations. Previous affiliations of Sheng Qi include Norwich University.
Papers
More filters
Journal ArticleDOI
An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused deposition modeling (FDM) 3D printing
TL;DR: Results indicated that interplay of the miscibility between excipients in the blends, the solubility of the materials in the dissolution media and the degree of fusion between the printed strips during FDM process can be used to manipulate the drug release rate of the dispersions.
Journal ArticleDOI
Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.
TL;DR: The study has indicated that the dispersion of the drug in the polymer may be complex in terms of both physical form and spatial distribution, with potential ramifications for stability and dissolution kinetics.
Journal ArticleDOI
Physicochemical Properties of the Amorphous Drug, Cast Films, and Spray Dried Powders to Predict Formulation Probability of Success for Solid Dispersions: Etravirine
Ilse Weuts,Frederic Van Dycke,Jody Firmin Marceline Voorspoels,Steve De Cort,Sigrid Stokbroekx,Ruud Leemans,Marcus E. Brewster,Dawei Xu,Brigitte E. Segmuller,Ya Tsz A. Turner,Clive J. Roberts,Martyn C. Davies,Sheng Qi,Duncan Q.M. Craig,Mike Reading +14 more
TL;DR: In this paper, a three part strategy is suggested to predict early formulateability of these systems, including an assessment of the amorphous form, a study of binary drug/carrier cast films and the evaluation of a powder of the drug and polymer processed in a manner relevant to the intended final dosage form.
PHARMACEUTICAL TECHNOLOGY Physicochemical Properties of the Amorphous Drug, Cast Films, and Spray Dried Powders to Predict Formulation Probability of Success for Solid Dispersions: Etravirine
Ilse Weuts,Frederic Van Dycke,Jody Firmin Marceline Voorspoels,Steve De Cort,Sigrid Carl Maria Stokbroekx,Ruud Leemans,Marcus E. Brewster,Dawei Xu,Brigitte E. Segmuller,Ya Tsz A. Turner,Clive J. Roberts,Martyn C. Davies,Sheng Qi,Mike Reading,Johnson Pharmaceutical R D +14 more
TL;DR: A three part strategy is suggested to predict early formulate-ability of a recently approved solid dispersion-based product, Intelence® (etravirine), suggesting a correlation between the glass forming ability and stability of the amorphous drug and the nature of the final formulation.
Journal ArticleDOI
Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament.
TL;DR: The screening method developed showed, with statistical significance and reproducibility, the ability to predetermine the feedability of extruded filaments into an FDM printer.