S
Shengfu Li
Researcher at Sichuan University
Publications - 74
Citations - 1508
Shengfu Li is an academic researcher from Sichuan University. The author has contributed to research in topics: Transplantation & Mesenchymal stem cell. The author has an hindex of 18, co-authored 71 publications receiving 1250 citations.
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Journal ArticleDOI
HIF-1α protects against oxidative stress by directly targeting mitochondria.
Hong-Sheng Li,Yanni Zhou,Lu Li,Shengfu Li,Dan Long,Xuelu Chen,Jia-Bi Zhang,Li Feng,Youping Li +8 more
TL;DR: Examining the subcellular localization of HIF-1α in human cells and identifying a small fraction that translocated to the mitochondria after exposure to hypoxia or H2O2 treatment suggested that mitochondrial Hif-1 α protects against oxidative stress induced-apoptosis independently of its well-known role as a transcription factor.
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Histidine-tryptophan-ketoglutarate solution vs. University of Wisconsin solution for liver transplantation: A systematic review
TL;DR: There was no statistically significant difference of effects (except bile production) between HTK and UW, but trends were documented in some studies for the superiority of HTK in biliary tract flush, prevention of biliary complications, and cost saving.
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An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria.
Xiao-Qing Qiu,He Wang,X.F. Lu,Jie Zhang,Shengfu Li,Gang Cheng,Lin Wan,Li Yang,Jun-Yong Zuo,Yu-Qi Zhou,Hai-Yun Wang,Xin Cheng,Su-Hua Zhang,Zheng-Rong Ou,Zi-Cheng Zhong,Jingqiu Cheng,Youping Li,George Y. Wu +17 more
TL;DR: The results suggest that these types of chimeric peptides may be of value as antibiotics against specific bacterial infections.
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The Protective Mechanism of Ligustrazine Against Renal Ischemia/Reperfusion Injury
TL;DR: Ligustrazine protects murine kidney from warm ischemia/reperfusion injury, probably via reducing oxidative stress, inhibiting cell apoptosis, decreasing neutrophils infiltration, and suppressing the overexpression of TNF-α and ICAM-1 levels.
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Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery
TL;DR: Conjugation of AMPs to bombesin might be an alternative approach for targeted cancer therapy and selectively induced cell death in cancer cells in vitro with the IC50 ranging from 10 to 15 μmol/L, which was about 6–10 times lower than the IC 50 for normal cells.