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Shiming Dong
Publications - 3
Citations - 28
Shiming Dong is an academic researcher. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 1 publications receiving 19 citations.
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Assessment of the quality and structural integrity of a complex glycoprotein mixture following extraction from the formulated biopharmaceutical drug product.
Cuihua Liu,Shiming Dong,Xiao-Jin Xu,Yan Yin,Zachary Shriver,Ishan Capila,James R. Myette,Ganesh Venkataraman +7 more
TL;DR: It is demonstrated that it is possible to effectively extract the active pharmaceutical ingredient from a formulated biological drug product in a manner that is consequently sufficient for its use in comparability studies.
Journal ArticleDOI
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway
Qianqian Huang,Chen Zhang,Shiming Dong,Jun-ling Han,Sihao Qu,Tianshu Xie,Hai-bo Zhao,Yuanyuan Shi +7 more
TL;DR: In this paper , an oleo-gum-resin isolated from Ferula assa-foetida root has been proven to possess antioxidative potential and neuroprotective effects, which is closely associated with the neurological disorders.
Journal ArticleDOI
Xiao-Luo-Wan treats propylthiouracil-induced goiter with hypothyroidism in rats through the PI3K-AKT/RAS pathways based on UPLC/MS and network pharmacology.
Shiming Dong,Qunying Liu,Miaocheng Jiang,Qihong Ma,Qianqian Huang,Tianhua Niu and Simin Liu,Yuan Li,Lei Ni,Yuanyuan Shi +8 more
TL;DR: In this paper , the authors investigated the therapeutic effect of XLW on propylthiouracil (PTU)-induced goiter with hypothyroidism in rats and uncovered the underlying molecular mechanism using ultra high-performance liquid chromatography-mass spectrometry (UPLC/MS), network pharmacology, and molecular docking simulations.