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Shinya Kodani
Researcher at Shizuoka University
Publications - 59
Citations - 836
Shinya Kodani is an academic researcher from Shizuoka University. The author has contributed to research in topics: Gene cluster & Peptide. The author has an hindex of 14, co-authored 54 publications receiving 706 citations. Previous affiliations of Shinya Kodani include Coventry Health Care & National Institute of Technology and Evaluation.
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Journal ArticleDOI
Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12
Takeshi Hosaka,Mayumi Ohnishi-Kameyama,Hideyuki Muramatsu,Kana Murakami,Yasuhisa Tsurumi,Yasuhisa Tsurumi,Shinya Kodani,Mitsuru Yoshida,Akihiko Fujie,Kozo Ochi +9 more
TL;DR: In this paper, it was shown that selection of drug-resistant bacterial mutants allows the discovery of antibacterial compounds, such as Piperidamycin, which is a previously unknown class of antibiotics.
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An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum
Keiko Ueda,Megumi Tsujimori,Shinya Kodani,Akiko Chiba,Masakazu Kubo,Kazuhiko Masuno,Atsushi Sekiya,Kaoru Nagai,Hirokazu Kawagishi +8 more
TL;DR: Three new compounds were isolated from the mushroom Hericium erinaceum and showed the protective activity against endoplasmic reticulum (ER) stress-dependent Neuro2a cell death, however, compounds 2 and 3 did not.
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Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22
Shinya Kodani,Joanna Bicz,Lijiang Song,Robert J. Deeth,Mayumi Ohnishi-Kameyama,Mitsuru Yoshida,Kozo Ochi,Gregory L. Challis +7 more
TL;DR: Comparative LC-MS/MS analyses of iron-deficient culture supernatants from wild type S. antibioticus showed that scabichelin is the metabolic product of the cryptic gene cluster, strongly suggesting that it functions as a siderophore.
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Isolation and structure determination of new siderophore albachelin from Amycolatopsis alba
TL;DR: Based on bioinformatics, the possible biosynthetic gene cluster involved in albachelin biosynthesis from the genome sequence of A. alba was deduced and the related genes including transporter for siderophore were found near the NRPS gene as a gene cluster.
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Isolation and Structure Determination of New Antibacterial Peptide Curacomycin Based on Genome Mining
TL;DR: A comparison of the antimicrobial activities of these two peptides indicated that the presence of chlorine in compound 1 was critical for its antimicrobial activity.