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Shirui Dong
Researcher at Jinan University
Publications - 9
Citations - 77
Shirui Dong is an academic researcher from Jinan University. The author has contributed to research in topics: Population & DNA methylation. The author has an hindex of 4, co-authored 9 publications receiving 35 citations.
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Journal ArticleDOI
Association Between SLC30A8 rs13266634 Polymorphism and Risk of T2DM and IGR in Chinese Population: A Systematic Review and Meta-Analysis.
Fang Dong,Fang Dong,Baohuan Zhang,Shaoling Zheng,Xiuxia Huang,Xiuben Du,Kehui Zhu,Xiaojing Chen,Jing Wu,Dandan Liu,Zihao Wen,Xiaoqian Zou,Yumei Liu,Shirui Dong,Fang-fang Zeng,Guang Yang,Chunxia Jing +16 more
TL;DR: It is demonstrated that SLC30A8 rs13266634 was a potential risk factor for type 2 diabetes mellitus (T2DM), and more studies should be performed to confirm the association between rs13 266634 polymorphism and IGR.
Journal ArticleDOI
Silica nanoparticles as an enhancer in the IL-1β-induced inflammation cycle of A549 cells.
Jing Wu,Yajing Han,Xiaoqian Zou,Kehui Zhu,Zichen Wang,Xiaohong Ye,Yumei Liu,Shirui Dong,Xiaojing Chen,Dandan Liu,Zihao Wen,Yao Wang,Shiqi Huang,Zixing Zhou,Chengli Zeng,Chuican Huang,Shaoling Zheng,Xiuben Du,Xiuxia Huang,Baohuan Zhang,Chunxia Jing,Guang Yang +21 more
TL;DR: It is indicated that nano-SiO2 had a toxic effect on A549 cells, and this effect could increase IL-1β on the A549 cell-induced inflammatory response.
Journal ArticleDOI
PM2.5 promotes replication of VSV by ubiquitination degradation of phospho-IRF3 in A549 cells.
Jing Wu,Kehui Zhu,Xiaolu Luo,Yajing Han,Baohuan Zhang,Zichen Wang,Shirui Dong,Xiaoqian Zou,Xiaojing Chen,Hongxuan Liu,Tianyuan Wu,Zhong Zheng,Yuefeng Xie,Jierong Zhao,Yumei Liu,Zihao Wen,Dandan Liu,Yao Wang,Shaoling Zheng,Xiuxia Huang,Chunxia Jing,Guang Yang +21 more
TL;DR: In the environment of PM2.5, an infection model in which VSV infected A549 cells was established, that mimics the state in which the antiviral innate immune pathways are activated after the respiratory system is infected with RNA viruses, PM 2.5 inhibited VSV-induced IFN-β expression and replication of the VSV viruses was promoted.
Journal ArticleDOI
Toxoplasma gondii Cathepsin C1 inhibits NF-κB signalling through the positive regulation of the HIF-1α/EPO axis.
Yumei Liu,Xiaoqian Zou,Meiling Ou,Xiaohong Ye,Baohuan Zhang,Tianyuan Wu,Shirui Dong,Xiaojing Chen,Hongxuan Liu,Zhong Zheng,Jierong Zhao,Jing Wu,Dandan Liu,Zihao Wen,Yao Wang,Shaoling Zheng,Kehui Zhu,Xiuxia Huang,Xiuben Du,Jiayu Liang,Xiaolu Luo,Yuefeng Xie,Min Wu,Congying Lu,Xin Xie,Kailiang Liu,Ying Yuting,Guolong Qi,Chunxia Jing,Guang Yang +29 more
TL;DR: This study identified a previously unrecognized role of CPC1 in the negative regulation of NF-κB activation through positive regulation of the HIF-1α/EPO axis and for the first time, CPC1 was shown to play an important role in immune evasion during T. gondii infection.
Journal ArticleDOI
Association Analysis of NLRP3 Inflammation-Related Gene Promotor Methylation as Well as Mediating Effects on T2DM and Vascular Complications in a Southern Han Chinese Population
Zixing Zhou,Lijun Wang,Zihao Wen,Shaoling Zheng,Xiaohong Ye,Dandan Liu,Jing Wu,Xiaoqian Zou,Yumei Liu,Yao Wang,Shirui Dong,Xiuxia Huang,Xiuben Du,Kehui Zhu,Xiaojing Chen,Shiqi Huang,Chengli Zeng,Yajing Han,Baohuan Zhang,Lihong Nie,Guang Yang,Chunxia Jing +21 more
TL;DR: Lower levels of AIM2 promoter total methylation might increase the risk of T2DM vascular complications, which merits further study to support the robustness of these findings.