Shiu-Fun Pang

TL;DR: The results indicate that orally administered Ginkgo biloba extract can protect the brain against changes leading to memory deficit through its effect on the cholinergic system.

TL;DR: Despite the usefulness of genetic relatedness in the subtype classification of G‐protein‐coupled melatonin receptors, functional correlation of molecular structure may ultimately prove the most comprehensive approach in melatonin receptor classification.

TL;DR: It was found that incubation of prolactinoma cells with 10−5, 10−4 or 10−3 m melatonin for 5 days inhibited cell growth and increased cell apoptosis, and melatonin increased caspase‐3 activity, Bax mRNA expression, and cytochrome c protein expression; Conversely, Bcl‐2 mRNA expression and mitochondrial membrane potential were inhibited by melatonin treatment.

TL;DR: The results suggest a specific melatonin receptor‐mediated action on the calcium channel of the embryonic chick myocyte and the melatonin‐induced increase in high‐voltage calcium current may increase myocyte contractility and enhance cardiac output.

TL;DR: The results suggest that alloxan‐induced diabetics may decrease pineal melatonin synthesis in rats by reducing the activity of hydroxyindole‐O‐methyltransferase, resulting in a decrease in pinealmelatonin secretion.