S
Shiv Kapoor
Researcher at University of Pennsylvania
Publications - 43
Citations - 7772
Shiv Kapoor is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cyclooxygenase & Transplantation. The author has an hindex of 27, co-authored 43 publications receiving 7506 citations. Previous affiliations of Shiv Kapoor include Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
Francesca Catella-Lawson,Muredach P. Reilly,Shiv Kapoor,Andrew J. Cucchiara,Susan DeMarco,Barbara Tournier,Sachin N. Vyas,Garret A. FitzGerald +7 more
TL;DR: The concomitant administration of ibuprofen but not rofecoxib, acetaminophen, or diclofenac antagonizes the irreversible platelet inhibition induced by aspirin, which may limit the cardioprotective effects of aspirin.
Journal ArticleDOI
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.
B. F. McAdam,Francesca Catella-Lawson,I. A. Mardini,Shiv Kapoor,John A. Lawson,Garret A. FitzGerald +5 more
TL;DR: In this paper, the effects of celecoxib on indices of COX-1-dependent platelet thromboxane (Tx) A2 and on systemic biosynthesis of prostacyclin in vivo were examined.
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Effect of testosterone treatment on bone mineral density in men over 65 years of age.
Peter J. Snyder,Helen Peachey,Peter Hannoush,Jesse A. Berlin,Louise Loh,John H. Holmes,Abdallah Dlewati,Janet Staley,Jill Santanna,Shiv Kapoor,Maurice F. Attie,John G. Haddad,Brian L. Strom +12 more
TL;DR: Increasing the serum testosterone concentrations of normal men over 65 yr of age to the midnormal range for young men did not increase lumbar spine bone density overall, but did increase it in those men with low pretreatment serumosterone concentrations.
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Effects of testosterone replacement in hypogonadal men
Peter J. Snyder,Helen Peachey,Jesse A. Berlin,Peter Hannoush,Ghada Haddad,Abdallah Dlewati,Jill Santanna,Louise Loh,David A. Lenrow,John H. Holmes,Shiv Kapoor,Atkinson Linda E,Brian L. Strom +12 more
TL;DR: It is concluded from this study that replacing testosterone in hypogonadal men increases bone mineral density of the spine and hip, fat-free mass, prostate volume, erythropoiesis, energy, and sexual function.
Journal Article
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids.
Francesca Catella-Lawson,Brendan McAdam,Briggs W. Morrison,Shiv Kapoor,Dean A. Kujubu,Lisa M. Antes,Kenneth C. Lasseter,Hui Quan,Barry J. Gertz,Garret A. FitzGerald +9 more
TL;DR: The data suggest that acute sodium retention by nonsteroidal anti-inflammatory drugs in healthy elderly subjects is mediated by the inhibition of Cox-2, whereas depression of GFR is due to inhibition ofcox-1.