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Shu Chu Shiesh
Researcher at National Cheng Kung University
Publications - 87
Citations - 3070
Shu Chu Shiesh is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Aptamer & Systematic evolution of ligands by exponential enrichment. The author has an hindex of 30, co-authored 87 publications receiving 2621 citations. Previous affiliations of Shu Chu Shiesh include National Tsing Hua University.
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Journal ArticleDOI
Correlation of serum levels of macrophage migration inhibitory factor with disease severity and clinical outcome in dengue patients.
Lien Cheng Chen,Huan Yao Lei,Ching Chuan Liu,Shu Chu Shiesh,Shun Hua Chen,Hsiao Sheng Liu,Yee Shin Lin,Shan Tair Wang,Huey Wen Shyu,Trai Ming Yeh +9 more
TL;DR: Serum levels of MIF were higher in all DHF patients who died than in DHF survivors and DF patients, and in addition to IL-6 and IL-10, elevated levels of serum MIF are a potential predictor of disease severity and clinical outcome in dengue patients.
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Beyond the Debye length in high ionic strength solution: direct protein detection with field-effect transistors (FETs) in human serum
Chia Ho Chu,Indu Sarangadharan,Abiral Regmi,Yen-Wen Chen,Chen Pin Hsu,Wen Hsin Chang,Geng Yen Lee,Jen-Inn Chyi,Chihchen Chen,Shu Chu Shiesh,Gwo-Bin Lee,Yu-Lin Wang +11 more
TL;DR: A new type of field-effect transistor (FET)-based biosensor is demonstrated to be able to overcome the problem of severe charge-screening effect caused by high ionic strength in solution and detect proteins in physiological environment.
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Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX).
TL;DR: A novel, automatic, miniature SELEX platform is presented that demonstrated fast screening of CRP aptamers and can be used as a powerful tool to select analyte-specific aptamer for biomedical applications.
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Serum total antioxidant capacity reflects severity of illness in patients with severe sepsis
Chia Chang Chuang,Shu Chu Shiesh,Chih Hsien Chi,Yi Fang Tu,Lien-I Hor,Chi Chang Shieh,Ming Feng Chen,Ming Feng Chen +7 more
TL;DR: Elevated serum TAC level may reflect clinical severity of sepsis, and serum uric acid levels appear to contribute importantly to the higher TAC levels observed in patients with severe sepsi.
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High sensitivity cardiac troponin I detection in physiological environment using AlGaN/GaN High Electron Mobility Transistor (HEMT) Biosensors.
Indu Sarangadharan,Abiral Regmi,Yen-Wen Chen,Chen Pin Hsu,Pei Chi Chen,Wen Hsin Chang,Geng Yen Lee,Jen-Inn Chyi,Shu Chu Shiesh,Gwo-Bin Lee,Yu-Lin Wang +10 more
TL;DR: The development of a high sensitivity assay for the detection of cardiac troponin I using electrical double layer gated high field AlGaN/GaN HEMT biosensor demonstrates the potential of the method as a rapid, inexpensive, high sensitivity CVD biomarker assay.