Shuhua Deng

TL;DR: In this article, the authors analyzed the current status and developing trends in Gut microbiota research in the depression field through bibliometric and visual analysis, which may help researchers choose suitable cooperators or journals, and promote their research illustrating the underlying molecular mechanisms of depression, including its etiology, prevention, and treatment.

TL;DR: In this paper, a bibliometric analysis aimed to provide a first glimpse into the dysregulated kynurenine pathway (KP), an immune-inflammatory pathway, in the pathophysiology of mood disorders, including depression and bipolar disorder characterized by a low-grade chronic pro-inflammatory state.

TL;DR: Investigating the serum concentrations of olanzapine in relation to age, sex, and other factors in Chinese patients found patients characterized with a combination of factors may benefit from TDM for the adjustment of oanzapine dose to minimize adverse reactions.

TL;DR: This is the first report of the difference in urocanic acid, a compound reported to improve glutamate biosynthesis and release in the central nervous system, between healthy controls and patients with major depression.

TL;DR: Co-administration of pirfenidone with grapefruit juice resulted in modestly reduced overall oral absorption and significantly reduced peak concentrations compared to fasting, which was similar to effect of food ingestion, which should raise concerns for clinical efficacy and safety.