S
Shuning Guo
Publications - 4
Citations - 14
Shuning Guo is an academic researcher. The author has contributed to research in topics: Biology & Cancer research. The author has an hindex of 3, co-authored 4 publications receiving 14 citations.
Papers
More filters
Journal ArticleDOI
Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5
Ye Sun,Kun Yan,Yi Wang,Cheng Xu,Dan Wang,Wei Zhou,Shuning Guo,Yujie Han,Lei Tang,Yanqiu Shao,Shaobo Shan,Qiangfeng Cliff Zhang,Yujie Tang,Liwei Zhang,Qiaoran Xi +14 more
TL;DR: In this paper , the authors showed that activation of BMP signaling promotes the exit of diffuse intrinsic pontine glioma (DIPG) tumor cells from a stem-cell-like state to differentiation by epigenetically regulating CXXC5.
Journal ArticleDOI
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth
Yizheng Zhang,Chuchu Zhang,Jiehan Li,Mei-Xiu Jiang,Shuning Guo,Ge Yang,Lingling Zhang,Feng Wang,Shiqi Yi,Jiangang Wang,Yang Fu,Yingjie Zhang +11 more
TL;DR: In this paper , the effects of increasing PARP1 dependent cell death (parthanatos) induced by inhibiting AKT on cell proliferation were determined by CCK-8 assay, colony formation assay, Hoechst 33,258 staining and analysis of apoptotic cells by flow cytometry.
Journal ArticleDOI
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth
Yizheng Zhang,Chuchu Zhang,Jiehan Li,Mei-Xiu Jiang,Shuning Guo,Ge Yang,Lingling Zhang,Feng Wang,Shiqi Yi,Jiangang Wang,Yang Fu,Yingjie Zhang +11 more
TL;DR: In this article , the effects of increasing PARP1 dependent cell death (parthanatos) induced by inhibiting AKT on cell proliferation were determined by CCK-8 assay, colony formation assay, Hoechst 33,258 staining and analysis of apoptotic cells by flow cytometry.
Journal ArticleDOI
Staged and repeated drought-induced regulation of phenylpropanoid synthesis confers tolerance to a water deficit environment in Camellia sinensis
Chenyu Shao,Jianjiao Chen,Zhidong Lv,Xizhi Gao,Shuning Guo,Suhang Yao,Zhida Chen,Yan-Hong Kang,Jianan Huang,Zhong Liu,Chengwen Shen +10 more
TL;DR: In this article , the authors investigated specialized metabolic drought responses in Chinese tea and found that the passive transfer of metabolites and upregulation of biosynthesis rates combined to regulate metabolite levels in tea plants under drought, ultimately reducing the levels of toxic oxygen radicals.