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Shunsuke Ando
Researcher at National Institute of Radiological Sciences
Publications - 6
Citations - 631
Shunsuke Ando is an academic researcher from National Institute of Radiological Sciences. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 5, co-authored 6 publications receiving 587 citations.
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Journal ArticleDOI
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
Ryoko Araki,Masahiro Uda,Yuko Hoki,Misato Sunayama,Miki Nakamura,Shunsuke Ando,Mayumi Sugiura,Hisashi Ideno,Hisashi Ideno,Akemi Shimada,Akira Nifuji,Akira Nifuji,Masumi Abe +12 more
TL;DR: Limited immunogenicity of transplanted cells differentiated from iPSCs and ES cells is suggested, suggesting limited immune responses in transplant recipients even when iPSC-derived differentiated cells are transplanted.
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Induced Pluripotent Stem Cell Generation-Associated Point Mutations Arise during the Initial Stages of the Conversion of These Cells
Mayumi Sugiura,Yasuji Kasama,Ryoko Araki,Yuko Hoki,Misato Sunayama,Masahiro Uda,Miki Nakamura,Shunsuke Ando,Masumi Abe +8 more
TL;DR: Strong evidence is obtained that iPSC-generation-associated point mutations occur frequently in a transversion-predominant manner just after the onset of cell lineage conversion, and a possible approach for establishing iPSCs with fewer point mutations is suggested.
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Crucial role of c-Myc in the generation of induced pluripotent stem cells.
Ryoko Araki,Yuko Hoki,Masahiro Uda,Miki Nakamura,Yuko Jincho,Chihiro Tamura,Misato Sunayama,Shunsuke Ando,Mayumi Sugiura,Mitsuaki A. Yoshida,Yasuji Kasama,Masumi Abe +11 more
TL;DR: The effects of c‐Myc transduction on the generation of iPSCs from an inbred mouse strain using a genome integration‐free vector is investigated to exclude the effects of the genetic background and the genomic integration of exogenous genes.
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Conversion of ancestral fibroblasts to induced pluripotent stem cells.
Ryoko Araki,Yuko Jincho,Yuko Hoki,Miki Nakamura,Chihiro Tamura,Shunsuke Ando,Yasuji Kasama,Masumi Abe +7 more
TL;DR: This is the first report to directly observe a cell lineage conversion of somatic cells to stem cells and provides a critical new insight into the “black box” of iPSCs, that is, the first three days of their generation.
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Generation of genome integration-free induced pluripotent stem cells from fibroblasts of C57BL/6 mice without c-Myc transduction.
Yuko Jincho,Ryoko Araki,Ryoko Araki,Yuko Hoki,Chihiro Tamura,Miki Nakamura,Miki Nakamura,Shunsuke Ando,Yasuji Kasama,Masumi Abe +9 more
TL;DR: Mouse strain-dependent differences in the c-Myc dependence for iPSC generation and the successful generation of genome integration-free iPSCs without c- myc transduction using C57BL/6 mouse embryonic fibroblasts are reported.