Institution
National Institute of Radiological Sciences
About: National Institute of Radiological Sciences is a based out in . It is known for research contribution in the topics: Radiation therapy & Detector. The organization has 3802 authors who have published 9044 publications receiving 182621 citations.
Topics: Radiation therapy, Detector, Ion, Gene, Population
Papers published on a yearly basis
Papers
More filters
National Institutes of Health1, Imperial College London2, Aarhus University3, University of Oxford4, University of Wisconsin-Madison5, University of Toronto6, University of California, Los Angeles7, Columbia University8, National Institute of Radiological Sciences9, University of Michigan10, University of Copenhagen11, University of Turku12, VU University Amsterdam13, Brookhaven National Laboratory14, Pfizer15, Washington University in St. Louis16, Indiana University – Purdue University Indianapolis17, University of Pittsburgh18, University of British Columbia19, Emory University20, Johns Hopkins University21, Yale University22
TL;DR: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
Abstract: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
1,858 citations
TL;DR: The fourth version of the Japanese Evaluated Nuclear Data Library has been produced in cooperation with the Japanese Nuclear Data Committee as mentioned in this paper, and much emphasis is placed on the improvement of the original library.
Abstract: The fourth version of the Japanese Evaluated Nuclear Data Library has been produced in cooperation with the Japanese Nuclear Data Committee. In the new library, much emphasis is placed on the impro...
1,699 citations
TL;DR: In this paper, the authors studied wild-type and P301S mutant human tau transgenic (Tg) mice and found that tangle formation was preceded by microglial activation.
1,565 citations
Georgetown University Medical Center1, University of Modena and Reggio Emilia2, Johns Hopkins University3, University of Louisville4, French Institute of Health and Medical Research5, Martin Luther University of Halle-Wittenberg6, University of Miami7, University of Bristol8, Tel Aviv University9, National Institute of Radiological Sciences10
TL;DR: Translocator protein (18kDa) is proposed as a new name, regardless of the subcellular localization of the protein, to represent more accurately its sub cellular role (or roles) and putative tissue-specific function (or functions).
1,264 citations
TL;DR: The high expression level of HLF mRNA in the O2 delivery system of developing embryos and adult organs suggests that in a normoxic state, HLF regulates gene expression of VEGF, various glycolytic enzymes, and others driven by the HRE sequence, and may be involved in development of blood vessels and the tubular system of lung.
Abstract: We have isolated and characterized a cDNA for a novel Per-Arnt/AhR-Sim basic helix–loop–helix (bHLH-PAS) factor that interacts with the Ah receptor nuclear translocator (Arnt), and its predicted amino acid sequence exhibits significant similarity to the hypoxia-inducible factor 1α (HIF1α) and Drosophila trachealess (dTrh) gene product. The HIF1α-like factor (HLF) encoded by the isolated cDNA bound the hypoxia-response element (HRE) found in enhancers of genes for erythropoietin, vascular endothelial growth factor (VEGF), and various glycolytic enzymes, and activated transcription of a reporter gene harboring the HRE. Although transcription-activating properties of HLF were very similar to those reported for HIF1α, their expression patterns were quite different between the two factors; HLF mRNA was most abundantly expressed in lung, followed by heart, liver, and other various organs under normoxic conditions, whereas HIF1α mRNA was ubiquitously expressed at much lower levels. In lung development around parturition, HLF mRNA expression was markedly enhanced, whereas that of HIF1α mRNA remained apparently unchanged at a much lower level. Moreover, HLF mRNA expression was closely correlated with that of VEGF mRNA. Whole mount in situ hybridization experiments demonstrated that HLF mRNA was expressed in vascular endothelial cells at the middle stages (9.5 and 10.5 days postcoitus) of mouse embryo development, where HIF1α mRNA was almost undetectable. The high expression level of HLF mRNA in the O2 delivery system of developing embryos and adult organs suggests that in a normoxic state, HLF regulates gene expression of VEGF, various glycolytic enzymes, and others driven by the HRE sequence, and may be involved in development of blood vessels and the tubular system of lung.
1,035 citations
Authors
Showing all 3802 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Masatoshi Nei | 114 | 302 | 271704 |
| Shunichi Fukuzumi | 111 | 1256 | 52764 |
| Wim J.G. Oyen | 96 | 788 | 39542 |
| Wei Zhang | 96 | 1404 | 43392 |
| David J. Chen | 94 | 303 | 32921 |
| Hiroshi Suzuki | 91 | 1167 | 35256 |
| Kenji Hashimoto | 86 | 820 | 32020 |
| Penny A. Jeggo | 86 | 217 | 26115 |
| Takahiro Nakamura | 83 | 524 | 26696 |
| Nobuhiro Nishiyama | 81 | 269 | 21910 |
| Yukihiko Kitamura | 80 | 419 | 37965 |
| Motomu Kanai | 79 | 521 | 18661 |
| Naoki Yasuda | 77 | 345 | 32880 |
| Masahiro Yamamoto | 77 | 434 | 33443 |
| Naohiko Seki | 74 | 381 | 18648 |