S
Sijun Dong
Researcher at Chinese Academy of Sciences
Publications - 82
Citations - 2961
Sijun Dong is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Chemistry. The author has an hindex of 29, co-authored 75 publications receiving 2336 citations. Previous affiliations of Sijun Dong include National Institute of Advanced Industrial Science and Technology & American Hotel & Lodging Educational Institute.
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Journal ArticleDOI
Biological impact of environmental polycyclic aromatic hydrocarbons (ePAHs) as endocrine disruptors
TL;DR: The findings of the bioassays have demonstrated that ePAHs have the ability to affect the endocrine systems of humans and animals, and standardized assay protocols for pathway-based assessments are considered to be important to overcome these issues.
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Bisphenol A induces a rapid activation of Erk1/2 through GPR30 in human breast cancer cells
TL;DR: GPR30 plays an important role in the BPA-induced activation of Erk1/2 in a manner distinguishable from that in ERα-mediated signaling.
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Exposure to DEHP and MEHP from hatching to adulthood causes reproductive dysfunction and endocrine disruption in marine medaka (Oryzias melastigma).
TL;DR: Results indicate that exposure to DEHP and MEHP from hatching to adulthood causes endocrine disruption with sex-specific effects in marine medaka, with males being more sensitive than females.
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Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells.
Yi Lin,Xiaohua Sun,Ling Qiu,Jie Wei,Qiansheng Huang,Chao Fang,Ting Ye,Mei Kang,Heqing Shen,Sijun Dong +9 more
TL;DR: Findings provide strong evidence that BPA triggers INS-1 cells dysfunction and apoptosis may be meditated via the mitochondrial pathway.
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Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease.
Yi Lin,Dongxiao Ding,Qiansheng Huang,Qiong Liu,Haoyang Lu,Yanyang Lu,Yulang Chi,Xia Sun,Guozhu Ye,Huimin Zhu,Jie Wei,Sijun Dong +11 more
TL;DR: In this article, BPA-induced hepatic steatosis and lipid accumulation were associated with decreased expression of miR-192, upregulation of SREBF1 and a series of genes involved in de novo lipogenesis.