Über die Adsorption in Lösungen

Droplet based microfluidics is a rapidly growing interdisciplinary field of research combining soft matter physics, biochemistry and microsystems engineering. Its applications range from fast analytical systems or the synthesis of advanced materials to protein crystallization and biological assays for living cells. Precise control of droplet volumes and reliable manipulation of individual droplets such as coalescence, mixing of their contents, and sorting in combination with fast analysis tools allow us to perform chemical reactions inside the droplets under defined conditions. In this paper, we will review available drop generation and manipulation techniques. The main focus of this review is not to be comprehensive and explain all techniques in great detail but to identify and shed light on similarities and underlying physical principles. Since geometry and wetting properties of the microfluidic channels are crucial factors for droplet generation, we also briefly describe typical device fabrication methods in droplet based microfluidics. Examples of applications and reaction schemes which rely on the discussed manipulation techniques are also presented, such as the fabrication of special materials and biophysical experiments.

https://iopscience.iop.org/article/10.1088/0034-4885/75/1/016601/pdf

Droplet based microfluidics

Continuous-flow liquid phase oxidation chemistry in microreactors receives a lot of attention as the reactor provides enhanced heat and mass transfer characteristics, safe use of hazardous oxidants, high interfacial areas, and scale-up potential. In this review, an up-to-date overview of both technological and chemical aspects of liquid phase oxidation chemistry in continuous-flow microreactors is given. A description of mass and heat transfer phenomena is provided and fundamental principles are deduced which can be used to make a judicious choice for a suitable reactor. In addition, the safety aspects of continuous-flow technology are discussed. Next, oxidation chemistry in flow is discussed, including the use of oxygen, hydrogen peroxide, ozone and other oxidants in flow. Finally, the scale-up potential for continuous-flow reactors is described.

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Liquid phase oxidation chemistry in continuous-flow microreactors

In this work, we have systematically analyzed the scaling law of droplet formation by cross-flow shear method in T-junction microfluidic devices The droplet formation mechanisms can be distinguished by the capillary number for the continuous phase (Cac), which are the squeezing regime (Cac < 0002), dripping regime (001 < Cac < 03), and the transient regime (0002 < Cac< 001) Three corresponding correlations have been suggested in the different range of Cac In the dripping regime, we developed a modified capillary number for the continuous phase (Cac′) by considering the influence of growing droplet size on the continuous phase flow rate And the modified model could predict droplet diameter more accurately In the squeezing regime, the final plug length was contributed by the growth and ‘squeeze’ stages based on the observation of dynamic break-up process In the transient regime, we firstly suggested a mathematical model by considering the influences of the above two mechanisms The correlations should be very useful for the application of controlling droplet size in T-junction microfluidic devices

Correlations of droplet formation in T-junction microfluidic devices: from squeezing to dripping

Continuous-flow photochemistry is used increasingly by researchers in academia and industry to facilitate photochemical processes and their subsequent scale-up. However, without detailed knowledge concerning the engineering aspects of photochemistry, it can be quite challenging to develop a suitable photochemical microreactor for a given reaction. In this review, we provide an up-to-date overview of both technological and chemical aspects associated with photochemical processes in microreactors. Important design considerations, such as light sources, material selection, and solvent constraints are discussed. In addition, a detailed description of photon and mass-transfer phenomena in microreactors is made and fundamental principles are deduced for making a judicious choice for a suitable photomicroreactor. The advantages of microreactor technology for photochemistry are described for UV and visible-light driven photochemical processes and are compared with their batch counterparts. In addition, different scale-up strategies and limitations of continuous-flow microreactors are discussed.

Photochemical transformations accelerated in continuous-flow reactors : basic concepts and applications

Ceramic nanocomposite membranes and membrane fouling: A review.

Enhancement of mass transfer performance of liquid–liquid system by droplet flow in microchannels

Degradation of tetracycline by medium pressure UV-activated peroxymonosulfate process: Influencing factors, degradation pathways, and toxicity evaluation

Simiao Li

Papers

Ceramic nanocomposite membranes and membrane fouling: A review.

Enhancement of mass transfer performance of liquid–liquid system by droplet flow in microchannels

Degradation of tetracycline by medium pressure UV-activated peroxymonosulfate process: Influencing factors, degradation pathways, and toxicity evaluation

Drop dispenser in a cross-junction microfluidic device : Scaling and mechanism of break-up

Gas–liquid flow in T-junction microfluidic devices with a new perpendicular rupturing flow route